2. Gene
  3. TMEM176B - transmembrane protein 176B Gene

TMEM176B - transmembrane protein 176B Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as LR8; MS4B2

Gene ID: 28959 | Gene type: protein coding

About TMEM176B

Cytogenetic location: 7q36.1 Genomic coordinates (GRCh38): 7:150,791,301-150,801,360 (from NCBI)

This gene has 6 transcripts (splice variants), 93 orthologues and 1 paralogue. Broad expression in liver (RPKM 288.9), kidney (RPKM 126.6) and 16 other tissues.

Summary

Predicted to be involved in negative regulation of dendritic cell differentiation. Predicted to be located in nuclear membrane. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]

TMEM176B Products(6)

mRNA Protein Name
NM_001101311.2 NP_001094781.1 transmembrane protein 176B isoform a
NM_001101312.2 NP_001094782.1 transmembrane protein 176B isoform a
NM_001101314.2 NP_001094784.1 transmembrane protein 176B isoform b
NM_001362691.2 NP_001349620.1 transmembrane protein 176B isoform c
NM_001362692.2 NP_001349621.1 transmembrane protein 176B isoform c
NM_014020.4 NP_054739.3 transmembrane protein 176B isoform a
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

TMEM176B Protein Structure

CD20

CD20: CD20-like family (66 - 228)

  • 0
  • 100
  • 200
  • 270 a.a.
Protein Preferred Names Protein Names

transmembrane protein 176B

LR8-like protein

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS14685 TMEM176B Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus TMEM176B RGD RGD:708403
Felis catus TMEM176B VGNC VGNC:66293
Mus musculus TMEM176B MGD MGI:1916348
Macaca mulatta TMEM176B VGNC VGNC:79817
Canis familiaris TMEM176B VGNC VGNC:47502
Bos taurus TMEM176B VGNC VGNC:36001