2. Gene
  3. Cd47 - Cd47 molecule Gene

Cd47 - Cd47 molecule Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Itgp

Gene ID: 29364 | Gene type: protein coding

About Cd47

Summary

Enables protein binding activity involved in heterotypic cell-cell adhesion. Involved in several processes, including cellular response to cytokine stimulus; positive regulation of monocyte extravasation; and regulation of phagocytosis. Located in cell surface. Orthologous to human CD47 (CD47 molecule). [provided by Alliance of Genome Resources, Apr 2022]

Cd47 Products(1)

mRNA Protein Name
NM_019195.2 NP_062068.1 leukocyte surface antigen CD47 precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding involved in heterotypic cell-cell adhesion IPI
IPI: Inferred from physical interaction
16055727 RGD
Biological Process GO Annotation Evidence Reference Source
involved in cell migration IDA
IDA: Inferred from direct assay
12023387 RGD
involved in cellular response to interleukin-1 IMP
IMP: Inferred from mutant phenotype
12023387 RGD
involved in cellular response to type II interferon IMP
IMP: Inferred from mutant phenotype
12023387 RGD
involved in negative regulation of phagocytosis IMP
IMP: Inferred from mutant phenotype
21401967 RGD
involved in positive regulation of monocyte extravasation IMP
IMP: Inferred from mutant phenotype
12023387 RGD
involved in positive regulation of phagocytosis IMP
IMP: Inferred from mutant phenotype
23238794 RGD
involved in positive regulation of stress fiber assembly IMP
IMP: Inferred from mutant phenotype
12023387 RGD
involved in regulation of Fc receptor mediated stimulatory signaling pathway IMP
IMP: Inferred from mutant phenotype
21401967 RGD
Cellular Component GO Annotation Evidence Reference Source
located in cell surface IDA
IDA: Inferred from direct assay
12023387 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

leukocyte surface antigen CD47

CD47 antigen (Rh-related antigen, integrin-associated signal transducer)

IAP

integrin-associated protein

Recombinant Cd47 Proteins

Cat. No. Product Name Accession Purity
HY-P75401 CD47 Protein, Rat (HEK293, His) P97829-1 (Q19-K140) ≥95%
HY-P75402 CD47 Protein, Rat (HEK293, Fc) P97829-1 (Q19-K140) ≥95%

Related Agents

Clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-16438 RRx-001 Inhibitor 99.16% Phase 3
Inhibitory Antibodies (6)
Cat. No. Product Name Effect
Purity Phase
HY-P99029 Magrolimab Inhibitor 96.40% Phase 3
HY-P99026 Lemzoparlimab Inhibitor / Phase 2
HY-P99777 Ontorpacept Inhibitor 99.57% Phase 2
HY-P99172 CC-90002 Inhibitor / Phase 1
HY-P990033 Anzurstobart Inhibitor 98.53% Phase 1
HY-P99533 Urabrelimab Inhibitor 98.49% Phase 1
Pre-clinical Phase
Bioactive Molecules (11)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-143224B NCGC00138783 TFA Inhibitor 99.71% Unkown
HY-P0144 Thrombospondin-1 (1016-1023) (human, bovine, mouse) Inhibitor 99.08% Unkown
HY-115983 DMUP Inhibitor ≥98.0% Unkown
HY-151132 Glutaminyl cyclases-IN-1 Inhibitor 98.21% Unkown
HY-143224 NCGC00138783 Inhibitor / Unkown
HY-P3968 Thrombospondin-1 (1016-1021) (human, bovine, mouse) / Unkown
HY-P10388 TAX2 peptide Inhibitor / Unkown
HY-143224A NCGC00138783 free base Inhibitor / Unkown
HY-P10420 RS17 Inhibitor / Unkown
HY-143225 NCGC00538431 Inhibitor / Unkown
HY-RS02250 CD47 Human Pre-designed siRNA Set A Inhibitor / Unkown
Inhibitory Antibodies (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P99175 KWAR 23 Inhibitor 99.80% Unkown
HY-P99706 Ligufalimab Inhibitor 98.81% Unkown
HY-P990132 Anti-Mouse/Rat/Human CD47/IAP Antibody (MIAP410) Inhibitor 95.00% Unkown
HY-P990131 Anti-Mouse CD47/IAP Antibody (MIAP301) Inhibitor 95.00% Unkown
HY-P990694 Zeripatamig Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cd47 NCBI NCBI:961
Macaca fascicularis Cd47 NCBI NCBI:102139846
Mus musculus Cd47 NCBI NCBI:16423
Macaca mulatta Cd47 NCBI NCBI:704980