2. Gene
  3. Limk2 - LIM domain kinase 2 Gene

Limk2 - LIM domain kinase 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Link2; Limk2b

Gene ID: 29524 | Gene type: protein coding

About Limk2

Primary_assembly 14: 78,218,063-78,286,007 reverse strand.mRatBN7.2:CM026987.1

This gene has 3 transcripts (splice variants), 205 orthologues, 23 paralogues and is associated with 1 phenotype. Biased expression in Brain (RPKM 42.8), Liver (RPKM 38.3) and 9 other tissues.

Summary

Enables protein serine/threonine kinase activity. Involved in protein phosphorylation. Located in nucleus. Orthologous to human LIMK2 (LIM domain kinase 2). [provided by Alliance of Genome Resources, Apr 2022]

Limk2 Products(1)

mRNA Protein Name
NM_024135.2 NP_077049.2 LIM domain kinase 2

Limk2 Protein Structure

LIM

LIM: cl02475 (11 - 64)

LIM2_LIMK2

LIM2_LIMK2: cd09465 (66 - 124)

PDZ

PDZ: pfam00595 (151 - 235)

PKc_like

PKc_like: cl21453 (336 - 595)

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  • 643 a.a.
Protein Preferred Names Protein Names

LIM domain kinase 2

LIM motif-containing protein kinase 2

LIMK-2

Related Agents

Pre-clinical Phase
Bioactive Molecules (11)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-18305 BMS-5 Inhibitor 99.51% Unkown
HY-18304 BMS-3 Inhibitor 99.46% Unkown
HY-122630 TH-257 Inhibitor 98.01% Unkown
HY-148063 DB0614 98.80% Unkown
HY-19352 T56-LIMKi Inhibitor 99.07% Unkown
HY-137346 DD-03-156 99.63% Unkown
HY-120025 CRT0105950 Inhibitor 99.91% Unkown
HY-151539 TH470 Inhibitor 99.57% Unkown
HY-128062 LIMK1 inhibitor BMS-4 Inhibitor ≥99.0% Unkown
HY-14227 LIMK-IN-1 Inhibitor 99.33% Unkown
HY-12659B LX7101 monohydrochloride Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Limk2 NCBI NCBI:3985