1. Gene
  2. F5 - coagulation factor V Gene

F5 - coagulation factor V Gene

Rattus norvegicus

Also known as Ac2-120

Gene ID: 304929 | Gene type: protein coding

About F5

Summary

Predicted to enable oxidoreductase activity. Involved in blood coagulation and response to vitamin K. Located in Golgi apparatus; endoplasmic reticulum; and extracellular space. Used to study membranoproliferative glomerulonephritis. Biomarker of hepatitis and portal hypertension. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); end stage renal disease; factor V deficiency; liver disease (multiple); and non-arteritic anterior ischemic optic neuropathy. Orthologous to human F5 (coagulation factor V). [provided by Alliance of Genome Resources, Apr 2022]

F5 Products(1)

mRNA Protein Name
NM_001047878.1 NP_001041343.1 coagulation factor V
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
involved in response to vitamin K IEP
IEP: Inferred from expression pattern
658784 RGD
Cellular Component GO Annotation Evidence Reference Source
located in extracellular region IDA
IDA: Inferred from direct assay
15172885 RGD
located in extracellular space IDA
IDA: Inferred from direct assay
3956160 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

coagulation factor V

coagulation factor V (proaccelerin, labile factor)

Orthologs Information

Species Symbol Source ID
Homo sapiens F5 NCBI NCBI:2153
Canis familiaris F5 NCBI NCBI:100685858
Macaca fascicularis F5 NCBI NCBI:102141482
Mus musculus F5 NCBI NCBI:14067
Leporidae F5 NCBI
Macaca mulatta F5 NCBI NCBI:704695