CENATAC - centrosomal AT-AC splicing factor Gene

Homo sapiens

Also known as MVA4; CCDC84; DLNB14

Gene ID: 338657 | Gene type: protein coding

About CENATAC

This gene has 10 transcripts (splice variants), 1 gene allele and 195 orthologues. Ubiquitous expression in skin (RPKM 3.1), spleen (RPKM 2.7) and 25 other tissues.

Summary

This gene encodes a protein thought to contain a coiled coil motif. No function has been determined for the encoded protein. A pseudogene of this gene is located on chromosome 20. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

CENATAC Products(1)

mRNA	Protein	Name
NM_198489.3	NP_940891.1	centrosomal AT-AC splicing factor

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	28514442	GOA

Biological Process GO Annotation	Evidence	Reference	Source
involved in chromosome separation	IMP IMP: Inferred from mutant phenotype	34009673	GOA
involved in mRNA splicing, via spliceosome	IMP IMP: Inferred from mutant phenotype	34009673	GOA
involved in negative regulation of centrosome duplication	IDA IDA: Inferred from direct assay	31722219	GOA
involved in negative regulation of centrosome duplication	IMP IMP: Inferred from mutant phenotype	34009673	GOA
involved in regulation of protein catabolic process	IMP IMP: Inferred from mutant phenotype	31722219	GOA

Cellular Component GO Annotation	Evidence	Reference	Source
located in centrosome	IDA IDA: Inferred from direct assay	31722219	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CENATAC Protein Structure

CCDC84

0
100
200
300
332 a.a.

Protein Preferred Names

Protein Names

centrosomal AT-AC splicing factor

coiled-coil domain containing 84

Related Diseases

Diseases

Alias

Intellectual Developmental Disorder, Autosomal Dominant 5

MRD5	Autosomal Dominant Non-Syndromic Intellectual Disability 5
Intellectual Disability, Autosomal Dominant 5	Mental Retardation, Autosomal Dominant 5
Autosomal Dominant Intellectual Developmental Disorder 5	Syngap1-Related Non-Syndromic Intellectual Disability
Autosomal Dominant Intellectual Disability 5	Syngap1 Syndrome
Syngap1-Related Nsid	Syngap1 Gene Mutation Linked To Intellectual Disability, Schizophrenia And Autism

Microcephalic Osteodysplastic Primordial Dwarfism, Type I

Taybi-Linder Syndrome	Brachymelic Primordial Dwarfism
Cephaloskeletal Dysplasia	Low-Birth-Weight Dwarfism With Skeletal Dysplasia
Microcephalic Osteodysplastic Primordial Dwarfism Type I	Osteodysplastic Primordial Dwarfism Type I
Primordial Microcephalic Dwarfism, Crachami Type	Osteodysplastic Primordial Dwarfism, Type 1
MOPD1	Mopd I
Mopd	Osteodysplastic Primordial Dwarfism, Type I
Tals	Microcephalic Osteodysplastic Primordial Dwarfism Type 1
Mopd 1	Microcephalic Osteodysplastic Primordial Dwarfism Types 1 And 3
Microcephalic Osteodysplastic Primordial Dwarfism Types I And Iii	Mopd Types I And Iii
Microcephalic Osteodysplastic Primordial Dwarfism, Taybi-Linder Type	Primordial Microcephalic Dwarfism Crachami Type
Dwarfism, Primordial, Osteodysplastic, Microcephalic, Type 1

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS02471	CENATAC Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	CENATAC	VGNC	VGNC:38862
Felis catus	CENATAC	VGNC	VGNC:60520
Mus musculus	CENATAC	MGD	MGI:2685960
Macaca mulatta	CENATAC	VGNC	VGNC:100909
Bos taurus	CENATAC	VGNC	VGNC:26922
Rattus norvegicus	CENATAC	RGD	RGD:1597440

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