2. Gene
  3. ATXN1L - ataxin 1 like Gene

ATXN1L - ataxin 1 like Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as BOAT; BOAT1

Gene ID: 342371 | Gene type: protein coding

About ATXN1L

Cytogenetic location: 16q22.2 Genomic coordinates (GRCh38): 16:71,845,976-71,857,328 (from NCBI)

This gene has 4 transcripts (splice variants), 184 orthologues and 1 paralogue. Ubiquitous expression in bone marrow (RPKM 17.2), kidney (RPKM 12.6) and 25 other tissues.

Summary

Predicted to enable DNA binding activity and RNA binding activity. Predicted to be involved in several processes, including learning or memory; regulation of transcription, DNA-templated; and social behavior. Predicted to act upstream of or within several processes, including lung alveolus development; negative regulation of transcription by RNA polymerase II; and positive regulation of hematopoietic stem cell proliferation. Located in nucleolus and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

ATXN1L Products(1)

mRNA Protein Name
NM_001137675.4 NP_001131147.1 ataxin-1-like
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
21475249 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ATXN1L Protein Structure

AXH

AXH: Ataxin-1 and HBP1 module (AXH) (469 - 581)

  • 0
  • 200
  • 400
  • 600
  • 689 a.a.
Protein Preferred Names Protein Names

ataxin-1-like

brother of ATXN1

ATXN1L Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra ATXN1L P0C7T5 FAM22F Homo sapiens B7ZLH0
Y2H Array
32296183
Intra ATXN1L P0C7T5 FAM22F Homo sapiens B7ZLH0
Y2H Prey Pooling
32296183
Intra ATXN1L P0C7T5 KRTAP19-7 Homo sapiens Q3SYF9
Validated Y2H
32296183
Intra ATXN1L P0C7T5 KRTAP19-7 Homo sapiens Q3SYF9
Y2H Prey Pooling
32296183
Intra ATXN1L P0C7T5 KRTAP19-7 Homo sapiens Q3SYF9
Y2H Array
32296183
Intra ATXN1L P0C7T5 KRTAP8-1 Homo sapiens Q8IUC2
Validated Y2H
32296183
Intra ATXN1L P0C7T5 KRTAP8-1 Homo sapiens Q8IUC2
Y2H Prey Pooling
32296183
Intra ATXN1L P0C7T5 KRTAP8-1 Homo sapiens Q8IUC2
Y2H Array
32296183
Intra ATXN1L P0C7T5 KRTAP11-1 Homo sapiens Q8IUC1
Validated Y2H
32296183
Intra ATXN1L P0C7T5 KRTAP11-1 Homo sapiens Q8IUC1
Y2H Array
32296183
Intra ATXN1L P0C7T5 KRTAP11-1 Homo sapiens Q8IUC1
Y2H Prey Pooling
32296183
Intra ATXN1L P0C7T5 LARP4B Homo sapiens Q92615
Y2H Array
32296183
Intra ATXN1L P0C7T5 LARP4B Homo sapiens Q92615
Y2H Prey Pooling
32296183
Intra ATXN1L P0C7T5 LARP4B Homo sapiens Q92615
Validated Y2H
32296183
Intra ATXN1L P0C7T5 PICALM Homo sapiens Q13492-3
Validated Y2H
32296183
Intra ATXN1L P0C7T5 PICALM Homo sapiens Q13492-3
Y2H Array
32296183
Intra ATXN1L P0C7T5 PICALM Homo sapiens Q13492-3
Y2H Prey Pooling
32296183
Intra ATXN1L P0C7T5 SHISA2 Homo sapiens Q6UWI4
Y2H Array
32296183
Intra ATXN1L P0C7T5 SHISA2 Homo sapiens Q6UWI4
Y2H Prey Pooling
32296183
Intra ATXN1L P0C7T5 SHISA2 Homo sapiens Q6UWI4
Validated Y2H
32296183
Intra ATXN1L P0C7T5 RBFOX2 Homo sapiens O43251-10
Y2H Array
32296183
Intra ATXN1L P0C7T5 RBFOX2 Homo sapiens O43251-10
Y2H Prey Pooling
32296183
Intra ATXN1L P0C7T5 USP54 Homo sapiens Q70EL1-9
Y2H Array
32296183
Intra ATXN1L P0C7T5 USP54 Homo sapiens Q70EL1-9
Validated Y2H
32296183
Intra ATXN1L P0C7T5 USP54 Homo sapiens Q70EL1-9
Y2H Prey Pooling
32296183
Intra ATXN1L P0C7T5 FAM168A Homo sapiens Q92567-2
Y2H Prey Pooling
32296183
Intra ATXN1L P0C7T5 FAM168A Homo sapiens Q92567-2
Validated Y2H
32296183
Intra ATXN1L P0C7T5 FAM168A Homo sapiens Q92567-2
Y2H Array
32296183
Intra ATXN1L P0C7T5 RBFOX1 Homo sapiens Q9NWB1-5
Validated Y2H
32296183
Intra ATXN1L P0C7T5 UNKL Homo sapiens Q9H9P5-5
Y2H Prey Pooling
32296183
Intra ATXN1L P0C7T5 UNKL Homo sapiens Q9H9P5-5
Validated Y2H
32296183
Intra ATXN1L P0C7T5 UNKL Homo sapiens Q9H9P5-5
Y2H Array
32296183
Intra ATXN1L P0C7T5 a0a1u9x8x8_human Homo sapiens A0A1U9X8X8
Y2H Prey Pooling
32296183
Intra ATXN1L P0C7T5 a0a1u9x8x8_human Homo sapiens A0A1U9X8X8
Y2H Array
32296183
Intra ATXN1L P0C7T5 FOXH1 Homo sapiens O75593
Y2H Prey Pooling
32296183
Intra ATXN1L P0C7T5 FOXH1 Homo sapiens O75593
Y2H Array
32296183
Intra ATXN1L P0C7T5 KRTAP21-2 Homo sapiens Q3LI59
Validated Y2H
32296183
Intra ATXN1L P0C7T5 KRTAP21-2 Homo sapiens Q3LI59
Y2H Array
32296183
Intra ATXN1L P0C7T5 KRTAP21-2 Homo sapiens Q3LI59
Y2H Prey Pooling
32296183
Intra ATXN1L P0C7T5 MEIS3 Homo sapiens Q99687-3
Validated Y2H
32296183
Intra ATXN1L P0C7T5 MEIS3 Homo sapiens Q99687-3
Y2H Array
32296183
Intra ATXN1L P0C7T5 MEIS3 Homo sapiens Q99687-3
Y2H Prey Pooling
32296183
Intra ATXN1L P0C7T5 TBX2 Homo sapiens Q13207
Validated Y2H
32296183
Intra ATXN1L P0C7T5 TBX2 Homo sapiens Q13207
Y2H Array
32296183
Intra ATXN1L P0C7T5 TBX2 Homo sapiens Q13207
Y2H Prey Pooling
32296183
Intra ATXN1L P0C7T5 MYOZ3 Homo sapiens Q8TDC0
Validated Y2H
32296183
Intra ATXN1L P0C7T5 RBPJ Homo sapiens Q06330
Y2H
21475249
Intra ATXN1L P0C7T5 RBPJ Homo sapiens Q06330
Pull Down
21475249
Intra ATXN1L P0C7T5 RBPJ Homo sapiens Q06330
Anti Tag CoIP
21475249
Intra ATXN1L P0C7T5 HLX Homo sapiens Q14774
Y2H Array
32296183
Intra ATXN1L P0C7T5 HLX Homo sapiens Q14774
Y2H Prey Pooling
32296183
Intra ATXN1L P0C7T5 HLX Homo sapiens Q14774
Validated Y2H
32296183
Intra ATXN1L P0C7T5 AGXT Homo sapiens P21549
Validated Y2H
32296183
Intra ATXN1L P0C7T5 SPMIP9 Homo sapiens Q96LM6
Y2H Prey Pooling
32296183
Intra ATXN1L P0C7T5 SPMIP9 Homo sapiens Q96LM6
Validated Y2H
32296183
Intra ATXN1L P0C7T5 SPMIP9 Homo sapiens Q96LM6
Y2H Array
32296183
Intra ATXN1L P0C7T5 METTL27 Homo sapiens Q8N6F8
Validated Y2H
32296183
Intra ATXN1L P0C7T5 METTL27 Homo sapiens Q8N6F8
Y2H Prey Pooling
32296183
Intra ATXN1L P0C7T5 METTL27 Homo sapiens Q8N6F8
Y2H Array
32296183
Intra ATXN1L P0C7T5 C1orf94 Homo sapiens Q6P1W5
Y2H Array
32296183
Intra ATXN1L P0C7T5 C1orf94 Homo sapiens Q6P1W5
Y2H Prey Pooling
32296183
Intra ATXN1L P0C7T5 C1orf94 Homo sapiens Q6P1W5
Validated Y2H
32296183
Intra ATXN1L P0C7T5 ARID5A Homo sapiens Q03989
Y2H Prey Pooling
32296183
Intra ATXN1L P0C7T5 ARID5A Homo sapiens Q03989
Validated Y2H
32296183
Intra ATXN1L P0C7T5 ARID5A Homo sapiens Q03989
Y2H Array
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Spinocerebellar Ataxia 1

Spinocerebellar Ataxia Type 1

SCA1

Olivopontocerebellar Atrophy I

Opca1

Opca4

Menzel Type Opca

Schut-Haymaker Type Opca

Spinocerebellar Atrophy I

Opca I

Olivopontocerebellar Atrophy Iv

Opca Iv

Cerebelloparenchymal Disorder I

Cpd1

Olivopontocerebellar Atrophy 1

Cerebelloparenchymal Disorder 1

Olivopontocerebellar Atrophy 4

Spinocerebellar Atrophy 1

Type 1 Spinocerebellar Ataxia

Spinocerebellar Ataxia-1

Ataxia, Spinocerebellar, Type 1
Omphalocele

Omphalocoele

Congenital Omphalocele

Exomphalos

Exumbilication
Autosomal Dominant Cerebellar Ataxia

Spinocerebellar Ataxia

Adca

Pierre Marie Cerebellar Ataxia

Ataxia, Spinocerebellar

Sca

Autosomal Dominant Spinocerebellar Ataxia

Spinocerebellar Ataxias
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS01255 ATXN1L Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus ATXN1L MGD MGI:3694797
Canis familiaris ATXN1L VGNC VGNC:38300
Rattus norvegicus ATXN1L RGD RGD:9319286
Macaca mulatta ATXN1L VGNC VGNC:99486
Bos taurus ATXN1L VGNC VGNC:26339