2. Gene
  3. EID3 - EP300 interacting inhibitor of differentiation 3 Gene

EID3 - EP300 interacting inhibitor of differentiation 3 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as NS4EB; NSE4B; NSMCE4B

Gene ID: 493861 | Gene type: protein coding

About EID3

Cytogenetic location: 12q23.3 Genomic coordinates (GRCh38): 12:104,303,739-104,305,205 (from NCBI)

This gene has 1 transcript (splice variant), 101 orthologues and 1 paralogue.

Summary

Predicted to be involved in DNA repair. Located in nucleolus and nucleoplasm. Part of Smc5-Smc6 complex. [provided by Alliance of Genome Resources, Apr 2022]

EID3 Products(1)

mRNA Protein Name
NM_001008394.3 NP_001008395.1 EP300-interacting inhibitor of differentiation 3
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
21364888 GOA
Cellular Component GO Annotation Evidence Reference Source
part of Smc5-Smc6 complex IDA
IDA: Inferred from direct assay
18086888 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

EID3 Protein Structure

Nse4-Nse3_bdg

Nse4-Nse3_bdg: Binding domain of Nse4/EID3 to Nse3-MAGE (89 - 140)

Nse4_C

Nse4_C: Nse4 C-terminal (239 - 330)

  • 0
  • 100
  • 200
  • 300
  • 333 a.a.
Protein Preferred Names Protein Names

EP300-interacting inhibitor of differentiation 3

E1A-like inhibitor of differentiation 3

Related Diseases

Diseases Alias
Floating-Harbor Syndrome

FLHS

Fhs

Pelletier-Leisti Syndrome

Short Stature With Delayed Bone Age, Expressive Language Delay, A Triangular Face With A Prominent Nose And Deep-Set Eyes

Leisti-Hollander-Rimoin Syndrome
Sotos Syndrome 2

Sotos2

Sotos Syndrome, Type 2
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS04236 EID3 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus EID3 RGD RGD:1597206
Mus musculus EID3 MGD MGI:1913591