PHOSPHO2 - phosphatase, orphan 2 Gene

Homo sapiens

Gene ID: 493911 | Gene type: protein coding

About PHOSPHO2

This gene has 8 transcripts (splice variants), 179 orthologues and 1 paralogue. Broad expression in testis (RPKM 6.7), prostate (RPKM 5.4) and 25 other tissues.

Summary

Predicted to enable Phosphatase activity. Predicted to be involved in dephosphorylation. [provided by Alliance of Genome Resources, Apr 2022]

PHOSPHO2 Products(5)

mRNA	Protein	Name
NM_001008489.4	NP_001008489.1	pyridoxal phosphate phosphatase PHOSPHO2
NM_001199285.2	NP_001186214.1	pyridoxal phosphate phosphatase PHOSPHO2
NM_001199286.2	NP_001186215.1	pyridoxal phosphate phosphatase PHOSPHO2
NM_001199287.2	NP_001186216.1	pyridoxal phosphate phosphatase PHOSPHO2
NM_001199288.2	NP_001186217.1	pyridoxal phosphate phosphatase PHOSPHO2

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	25416956	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

PHOSPHO2 Protein Structure

Put_Phosphatase

0
100
200
241 a.a.

Protein Preferred Names

Protein Names

pyridoxal phosphate phosphatase PHOSPHO2

PHOSPHO2 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	PHOSPHO2	Q8TCD6	JPH3	Homo sapiens	Q8WXH2	Y2H Array	32814053
Intra	PHOSPHO2	Q8TCD6	JPH3	Homo sapiens	Q8WXH2	Y2H Pooling	32814053
Intra	PHOSPHO2	Q8TCD6	JPH3	Homo sapiens	Q8WXH2	Validated Y2H	32814053
Intra	PHOSPHO2	Q8TCD6	VHL	Homo sapiens	P40337-2	Y2H Array	32814053
Intra	PHOSPHO2	Q8TCD6	VHL	Homo sapiens	P40337-2	Y2H Pooling	32814053
Intra	PHOSPHO2	Q8TCD6	VHL	Homo sapiens	P40337-2	Validated Y2H	32814053
Intra	PHOSPHO2	Q8TCD6	ATP5PF	Homo sapiens	P18859	Y2H Array	32296183
Intra	PHOSPHO2	Q8TCD6	ATP5PF	Homo sapiens	P18859	Y2H Prey Pooling	32296183
Intra	PHOSPHO2	Q8TCD6	C1QTNF2	Homo sapiens	Q9BXJ5	Y2H Prey Pooling	32296183
Intra	PHOSPHO2	Q8TCD6	C1QTNF2	Homo sapiens	Q9BXJ5	Validated Y2H	32296183
Intra	PHOSPHO2	Q8TCD6	C1QTNF2	Homo sapiens	Q9BXJ5	Y2H Array	32296183
Intra	PHOSPHO2	Q8TCD6	TSEN15	Homo sapiens	Q8WW01	Y2H Prey Pooling	32296183
Intra	PHOSPHO2	Q8TCD6	TSEN15	Homo sapiens	Q8WW01	Validated Y2H	32296183
Intra	PHOSPHO2	Q8TCD6	TSEN15	Homo sapiens	Q8WW01	Y2H Array	32296183
Intra	PHOSPHO2	Q8TCD6	WASHC3	Homo sapiens	Q9Y3C0	Validated Y2H	32296183
Intra	PHOSPHO2	Q8TCD6	WASHC3	Homo sapiens	Q9Y3C0	Y2H Array	32296183
Intra	PHOSPHO2	Q8TCD6	WASHC3	Homo sapiens	Q9Y3C0	Y2H Prey Pooling	32296183
Intra	PHOSPHO2	Q8TCD6	GKAP1	Homo sapiens	Q5VSY0	Y2H Prey Pooling	32296183
Intra	PHOSPHO2	Q8TCD6	GKAP1	Homo sapiens	Q5VSY0	Y2H Array	32296183
Intra	PHOSPHO2	Q8TCD6	NAB2	Homo sapiens	Q15742	Y2H Prey Pooling	32296183
Intra	PHOSPHO2	Q8TCD6	NAB2	Homo sapiens	Q15742	Y2H Array	32296183
Intra	PHOSPHO2	Q8TCD6	FLNA	Homo sapiens	P21333-2	Y2H Array	32296183
Intra	PHOSPHO2	Q8TCD6	FLNA	Homo sapiens	P21333-2	Y2H Prey Pooling	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases

Alias

Cone-Rod Dystrophy 2

Cone-Rod Dystrophy	CORD2
Cone-Rod Retinal Dystrophy	Rcrd2
Cone-Rod Retinal Dystrophy 2	Crd2
Cord	Crd
Retinal Cone-Rod Dystrophy	Cone-Rod Retinal Dystrophy-2
Retinal Cone-Rod Dystrophy 2	Tapetoretinal Degeneration
Cone-Rod Degeneration	Cone Rod Dystrophy
Dystrophy, Cone-Rod	Dystrophy, Cone-Rod, Type 2
Retinitis Pigmentosa	Retinitis Pigmentosa 2
Progressive Cone-Rod Dystrophy

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS10450	PHOSPHO2 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	PHOSPHO2	MGD	MGI:1920623
Rattus norvegicus	PHOSPHO2	RGD	RGD:1359274
Canis familiaris	PHOSPHO2	VGNC	VGNC:44506
Felis catus	PHOSPHO2	VGNC	VGNC:64152
Macaca mulatta	PHOSPHO2	VGNC	VGNC:99392
Bos taurus	PHOSPHO2	VGNC	VGNC:32843

Name
Email *

	Sorry, but the email address you supplied was invalid.