2. Gene
  3. GKAP1 - G kinase anchoring protein 1 Gene

GKAP1 - G kinase anchoring protein 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as FKSG21; GKAP42

Gene ID: 80318 | Gene type: protein coding

About GKAP1

Cytogenetic location: 9q21.32 Genomic coordinates (GRCh38): 9:83,739,425-83,817,769 (from NCBI)

This gene has 7 transcripts (splice variants) and 205 orthologues. Biased expression in testis (RPKM 88.6) and ovary (RPKM 4.2).

Summary

This gene encodes a protein that is highly similar to the mouse cGMP-dependent protein kinase anchoring protein 42kDa. The mouse protein has been found to localize with the Golgi and recruit cGMP-dependent protein kinase I alpha to the Golgi in mouse testes. It is thought to play a role in germ cell development. Transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]

GKAP1 Products(2)

mRNA Protein Name
NM_001135953.2 NP_001129425.1 G kinase-anchoring protein 1 isoform b
NM_025211.4 NP_079487.2 G kinase-anchoring protein 1 isoform a
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables identical protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

G kinase-anchoring protein 1

cGMP-dependent protein kinase anchoring protein 42kDa

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS05460 GKAP1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus GKAP1 VGNC VGNC:29387
Felis catus GKAP1 VGNC VGNC:62569
Mus musculus GKAP1 MGD MGI:1891694
Canis familiaris GKAP1 VGNC VGNC:41245
Rattus norvegicus GKAP1 RGD RGD:1306955