2. Gene
  3. Cbx7 - chromobox 7 Gene

Cbx7 - chromobox 7 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as D15Ertd417e; 1600014J01Rik

Gene ID: 52609 | Gene type: protein coding

About Cbx7

Summary

Enables chromatin binding activity; methylated histone binding activity; and single-stranded RNA binding activity. Acts upstream of or within sebaceous gland development. Located in heterochromatin and nucleus. Part of PRC1 complex. Is expressed in brain. Human ortholog(s) of this gene implicated in breast cancer; multiple myeloma; and myeloid leukemia. Orthologous to human CBX7 (chromobox 7). [provided by Alliance of Genome Resources, Apr 2022]

Cbx7 Products(1)

mRNA Protein Name
NM_144811.3 NP_659060.1 chromobox protein homolog 7
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables chromatin binding IDA
IDA: Inferred from direct assay
22056776 MGI
enables methylated histone binding IDA
IDA: Inferred from direct assay
16537902 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
20543829 MGI
enables single-stranded RNA binding IDA
IDA: Inferred from direct assay
16537902 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within sebaceous gland development IMP
IMP: Inferred from mutant phenotype
23870131 MGI
Cellular Component GO Annotation Evidence Reference Source
part of PRC1 complex IDA
IDA: Inferred from direct assay
19636380 MGI
located in heterochromatin IDA
IDA: Inferred from direct assay
16537902 MGI
located in nucleus IDA
IDA: Inferred from direct assay
16537902 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

chromobox protein homolog 7

chromobox homolog 7

Cbx7 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Cross
Cbx7 Q8VDS3 IGF2BP1 Homo sapiens Q9NZI8
Anti Tag CoIP
20543829
Cross
Cbx7 Q8VDS3 IGF2BP1 Homo sapiens Q9NZI8
TAP
20543829
Cross
Cbx7 Q8VDS3 MOV10 Homo sapiens Q9HCE1
TAP
20543829
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase
Bioactive Molecules (7)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-100832 UNC3866 Inhibitor 99.50% Unkown
HY-119344 MS37452 Inhibitor 99.81% Unkown
HY-126327 UNC4976 Antagonist / Unkown
HY-RS02014 CBX7 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-126327A UNC4976 TFA Antagonist ≥98.0% Unkown
HY-100832A UNC3866 TFA Inhibitor / Unkown
HY-125655 UNC-4219 TFA Control / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cbx7 NCBI NCBI:23492