STYK1 - serine/threonine/tyrosine kinase 1 Gene

Homo sapiens

Also known as NOK; SuRTK106

Gene ID: 55359 | Gene type: protein coding

About STYK1

Cytogenetic location: 12p13.2 Genomic coordinates (GRCh38): 12:10,618,923-10,674,052 (from NCBI)

This gene has 6 transcripts (splice variants), 219 orthologues and 32 paralogues. Biased expression in colon (RPKM 5.3), stomach (RPKM 4.5) and 13 other tissues.

Summary

Receptor Protein Tyrosine Kinases, like STYK1, play important roles in diverse cellular and developmental processes, such as cell proliferation, differentiation, and survival (Liu et al., 2004 [PubMed 15150103]).[supplied by OMIM, Mar 2008]

STYK1 Products(1)

mRNA	Protein	Name
NM_018423.3	NP_060893.2	tyrosine-protein kinase STYK1

STYK1 Protein Structure

Pkinase_Tyr

0
100
200
300
422 a.a.

Protein Preferred Names

Protein Names

tyrosine-protein kinase STYK1

novel oncogene with kinase domain

STYK1 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	STYK1	Q6J9G0	HSP90AB1	Homo sapiens	P08238	Pull Down	32707033
Intra	STYK1	Q6J9G0	HSP90AB1	Homo sapiens	P08238	Affinity Chrom	35384245
Intra	STYK1	Q6J9G0	GSK3B	Homo sapiens	P49841	Anti Tag CoIP	23010592

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases

Alias

Developmental And Epileptic Encephalopathy 34

DEE34	Epileptic Encephalopathy, Early Infantile, 34
Eiee34	Developmental And Epileptic Encephalopathy, 34
Early Infantile Epileptic Encephalopathy 34

Branchiootorenal Syndrome 1

Melnick-Fraser Syndrome	BOR1
Branchiootorenal Dysplasia	Branchiootorenal Syndrome 1, With Or Without Cataracts
Bor Syndrome 1	Branchiootorenal Dysplasia 1
Branchio-Oto-Renal Dysplasia 1	Branchio-Oto-Renal Syndrome Type 1
Branchiootorenal Syndrome, With/Without Cataract, Type 1	Branchio-Oto-Renal Syndrome

Cataract 11, Multiple Types

Cataract, Posterior Polar, 4	Ctpp4
Cpp4	Cataract 11 Multiple Types
CTRCT11	Cataract 11, Syndromic, Autosomal Recessive
Cataract 11 With Microphthalmia And Neurodevelopmental Abnormalities	Posterior Polar Cataract 4
Posterior Polar Cataract, 4	Cataract Posterior Polar 4
Syndromic Cataract 11	Cataract, Type 11, Multiple Types

Cervix Carcinoma

Cancer Of Cervix	Carcinoma Of Cervix
Carcinoma Cervix Uteri	Carcinoma Of The Cervix Uteri

Tinea Capitis

Dermatophytosis Of Scalp	Scalp Ringworm
Dermatophytosis Of Scalp Or Beard	Tinea Capitis Due To Trichophyton Rubrum
Trichophyton Rubrum Tinea Capitis

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13996	STYK1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	STYK1	VGNC	VGNC:65823
Bos taurus	STYK1	VGNC	VGNC:35451
Rattus norvegicus	STYK1	RGD	RGD:1564211
Mus musculus	STYK1	MGD	MGI:2141396
Macaca mulatta	STYK1	VGNC	VGNC:78165
Others	STYK1	NCBI

Name
Email *

	Sorry, but the email address you supplied was invalid.