Rybp - RING1 and YY1 binding protein Gene

Mus musculus

Also known as DEDAF; YEAF1; 2410018J24Rik

Gene ID: 56353 | Gene type: protein coding

About Rybp

Summary

Enables DNA binding activity and transcription corepressor activity. Acts upstream of or within negative regulation of transcription by RNA polymerase II. Located in nucleoplasm. Is expressed in several structures, including brain; early embryo; extraembryonic component; genitourinary system; and nose. Orthologous to human RYBP (RING1 and YY1 binding protein). [provided by Alliance of Genome Resources, Apr 2022]

Rybp Products(1)

mRNA	Protein	Name
NM_019743.3	NP_062717.2	RING1 and YY1-binding protein

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables DNA binding	IDA IDA: Inferred from direct assay	15574595	MGI
enables protein binding	IPI IPI: Inferred from physical interaction	10369680	MGI
enables transcription corepressor activity	IDA IDA: Inferred from direct assay	10369680	MGI

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within negative regulation of transcription by RNA polymerase II	IDA IDA: Inferred from direct assay	10369680	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in nucleoplasm	IDA IDA: Inferred from direct assay	10369680	MGI
located in nucleus	IDA IDA: Inferred from direct assay	10919273	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

RING1 and YY1-binding protein

DED-associated factor	Ring1 interactor Rybp
death effector domain-associated factor

Rybp Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	Rybp	Q8CCI5	Cbx2	Mus musculus	P30658	Pull Down	10369680
Intra	Rybp	Q8CCI5	Rnf2	Mus musculus	Q9CQJ4	Anti Bait CoIP	10369680
Intra	Rybp	Q8CCI5	Rnf2	Mus musculus	Q9CQJ4	Anti Bait CoIP	22325148
Intra	Rybp	Q8CCI5	Rnf2	Mus musculus	Q9CQJ4	Anti Tag CoIP	22325148
Intra	Rybp	Q8CCI5	Ring1	Mus musculus	O35730	Pull Down	10369680
Intra	Rybp	Q8CCI5	Ring1	Mus musculus	O35730	Anti Tag CoIP	22325148
Intra	Rybp	Q8CCI5	Ring1	Mus musculus	O35730	Anti Bait CoIP	10369680

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS12366	RYBP Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Rybp	NCBI	NCBI:23429

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