ABHD17C - abhydrolase domain containing 17C, depalmitoylase Gene

Homo sapiens

Also known as FAM108C1

Gene ID: 58489 | Gene type: protein coding

About ABHD17C

Cytogenetic location: 15q25.1 Genomic coordinates (GRCh38): 15:80,695,310-80,755,621 (from NCBI)

This gene has 5 transcripts (splice variants), 193 orthologues and 7 paralogues. Broad expression in colon (RPKM 37.1), stomach (RPKM 19.2) and 20 other tissues.

Summary

Enables palmitoyl-(protein) hydrolase activity. Involved in protein depalmitoylation. Predicted to be located in postsynaptic density. Predicted to be active in endosome membrane; glutamatergic synapse; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

ABHD17C Products(1)

mRNA	Protein	Name
NM_021214.2	NP_067037.1	alpha/beta hydrolase domain-containing protein 17C

ABHD17C Protein Structure

Abhydrolase_5

0
100
200
300
329 a.a.

Protein Preferred Names

Protein Names

alpha/beta hydrolase domain-containing protein 17C

abhydrolase domain-containing protein 17C

ABHD17C Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	ABHD17C	Q6PCB6	DNM2	Homo sapiens	P50570-2	Y2H Pooling	32814053
Intra	ABHD17C	Q6PCB6	DNM2	Homo sapiens	P50570-2	Validated Y2H	32814053
Intra	ABHD17C	Q6PCB6	DNM2	Homo sapiens	P50570-2	Y2H Array	32814053
Intra	ABHD17C	Q6PCB6	MECP2	Homo sapiens	P51608	Validated Y2H	32814053
Intra	ABHD17C	Q6PCB6	MECP2	Homo sapiens	P51608	Y2H Array	32814053
Intra	ABHD17C	Q6PCB6	MECP2	Homo sapiens	P51608	Y2H Pooling	32814053
Intra	ABHD17C	Q6PCB6	APBB2	Homo sapiens	Q92870-2	Validated Y2H	32814053
Intra	ABHD17C	Q6PCB6	APBB2	Homo sapiens	Q92870-2	Y2H Array	32814053
Intra	ABHD17C	Q6PCB6	APBB2	Homo sapiens	Q92870-2	Y2H Pooling	32814053
Intra	ABHD17C	Q6PCB6	TOR1A	Homo sapiens	O14656-2	Validated Y2H	32814053
Intra	ABHD17C	Q6PCB6	TOR1A	Homo sapiens	O14656-2	Y2H Array	32814053
Intra	ABHD17C	Q6PCB6	TOR1A	Homo sapiens	O14656-2	Y2H Pooling	32814053
Intra	ABHD17C	Q6PCB6	SMN1	Homo sapiens	Q16637	Validated Y2H	32814053
Intra	ABHD17C	Q6PCB6	SMN1	Homo sapiens	Q16637	Y2H Array	32814053
Intra	ABHD17C	Q6PCB6	SMN1	Homo sapiens	Q16637	Y2H Pooling	32814053
Intra	ABHD17C	Q6PCB6	PMP22	Homo sapiens	A0A6Q8PF08	Y2H Array	32814053
Intra	ABHD17C	Q6PCB6	PMP22	Homo sapiens	A0A6Q8PF08	Y2H Pooling	32814053
Intra	ABHD17C	Q6PCB6	PMP22	Homo sapiens	A0A6Q8PF08	Validated Y2H	32814053
Intra	ABHD17C	Q6PCB6	TOR1A	Homo sapiens	O14656	Y2H Array	32814053
Intra	ABHD17C	Q6PCB6	TOR1A	Homo sapiens	O14656	Validated Y2H	32814053
Intra	ABHD17C	Q6PCB6	TOR1A	Homo sapiens	O14656	Y2H Pooling	32814053
Intra	ABHD17C	Q6PCB6	A2M	Homo sapiens	P01023	Y2H Array	32814053
Intra	ABHD17C	Q6PCB6	A2M	Homo sapiens	P01023	Validated Y2H	32814053
Intra	ABHD17C	Q6PCB6	A2M	Homo sapiens	P01023	Y2H Pooling	32814053
Intra	ABHD17C	Q6PCB6	PHYH	Homo sapiens	O14832	Validated Y2H	32814053
Intra	ABHD17C	Q6PCB6	PHYH	Homo sapiens	O14832	Y2H Pooling	32814053
Intra	ABHD17C	Q6PCB6	PHYH	Homo sapiens	O14832	Y2H Array	32814053
Intra	ABHD17C	Q6PCB6	OPTN	Homo sapiens	Q96CV9	Validated Y2H	32814053
Intra	ABHD17C	Q6PCB6	OPTN	Homo sapiens	Q96CV9	Y2H Array	32814053
Intra	ABHD17C	Q6PCB6	OPTN	Homo sapiens	Q96CV9	Y2H Pooling	32814053

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS00092	ABHD17C Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	ABHD17C	RGD	RGD:1308210
Macaca mulatta	ABHD17C	VGNC	VGNC:69538
Bos taurus	ABHD17C	VGNC	VGNC:53931
Mus musculus	ABHD17C	MGD	MGI:1917428
Felis catus	ABHD17C	VGNC	VGNC:80773

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