2. Gene
  3. Gucy1a2 - guanylate cyclase 1 soluble subunit alpha 2 Gene

Gucy1a2 - guanylate cyclase 1 soluble subunit alpha 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 66012 | Gene type: protein coding

About Gucy1a2

Summary

Enables Guanylate Cyclase activity. Predicted to be involved in cGMP biosynthetic process and intracellular signal transduction. Predicted to act upstream of or within positive regulation of nitric oxide mediated signal transduction. Predicted to be located in cytosol. Orthologous to human GUCY1A2 (Guanylate Cyclase 1 soluble subunit alpha 2). [provided by Alliance of Genome Resources, Apr 2022]

Gucy1a2 Products(1)

mRNA Protein Name
NM_023956.1 NP_076446.1 guanylate cyclase soluble subunit alpha-2
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables guanylate cyclase activity IDA
IDA: Inferred from direct assay
11121588 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
11572861 RGD
enables protein-containing complex binding IPI
IPI: Inferred from physical interaction
9294115 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

guanylate cyclase soluble subunit alpha-2

GCS-alpha-2

guanylate cyclase 1, soluble, alpha 2

soluble guanylyl cyclase alpha2 subunit

Gucy1a2 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Cross
Gucy1a2 Q9WVI4 Dlg4 Mus musculus Q62108
Pull Down
17950729
Intra
Gucy1a2 Q9WVI4 Dlg4 Rattus norvegicus P31016
Pull Down
11572861
Intra
Gucy1a2 Q9WVI4 Dlg4 Rattus norvegicus P31016
Anti Bait CoIP
11572861
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS05919 GUCY1A2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gucy1a2 NCBI NCBI:2977