2. Gene
  3. TPD52 - tumor protein D52 Gene

TPD52 - tumor protein D52 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as D52; N8L; PC-1; PrLZ; hD52

Gene ID: 7163 | Gene type: protein coding

About TPD52

Cytogenetic location: 8q21.13 Genomic coordinates (GRCh38): 8:80,031,082-80,171,564 (from NCBI)

This gene has 29 transcripts (splice variants), 217 orthologues and 3 paralogues. Broad expression in colon (RPKM 43.8), prostate (RPKM 36.3) and 23 other tissues.

Summary

Enables calcium ion binding activity and protein homodimerization activity. Involved in B cell differentiation. Located in endoplasmic reticulum and perinuclear region of cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

TPD52 Products(9)

mRNA Protein Name
NM_001025252.3 NP_001020423.1 tumor protein D52 isoform 1
NM_001025253.3 NP_001020424.1 tumor protein D52 isoform 2
NM_001287140.2 NP_001274069.1 tumor protein D52 isoform 4
NM_001287142.2 NP_001274071.1 tumor protein D52 isoform 5
NM_001287143.2 NP_001274072.1 tumor protein D52 isoform 6
NM_001287144.2 NP_001274073.1 tumor protein D52 isoform 7
NM_001387779.1 NP_001374708.1 tumor protein D52 isoform 9
NM_001387780.1 NP_001374709.1 tumor protein D52 isoform 10
NM_005079.4 NP_005070.1 tumor protein D52 isoform 3
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables calcium ion binding IDA
IDA: Inferred from direct assay
15576473 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
9484778 GOA
enables protein homodimerization activity IDA
IDA: Inferred from direct assay
9484778 GOA
Biological Process GO Annotation Evidence Reference Source
involved in B cell differentiation IEP
IEP: Inferred from expression pattern
15576473 GOA
Cellular Component GO Annotation Evidence Reference Source
located in cytoplasm IDA
IDA: Inferred from direct assay
15576473 GOA
located in endoplasmic reticulum IDA
IDA: Inferred from direct assay
10942595 GOA
located in perinuclear region of cytoplasm IDA
IDA: Inferred from direct assay
16112108 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

TPD52 Protein Structure

TPD52

TPD52: Tumour protein D52 family (47 - 211)

  • 0
  • 100
  • 200
  • 224 a.a.
Protein Preferred Names Protein Names

tumor protein D52

prostate and colon associated protein

Related Diseases

Diseases Alias
Prostate Cancer

Prostate Carcinoma

Prostate Cancer, Familial

Prostate Neoplasm

Prostate Cancer, Somatic

Prostate Cancer, Susceptibility To

Prostatic Cancer

Prostatic Neoplasms

Hereditary Prostate Cancer

Prostatic Neoplasm

Cancer Of Prostate

Carcinoma Of Prostate

Familial Prostate Cancer

Familial Prostate Carcinoma

Malignant Tumor Of Prostate

Malignant Neoplasm Of Prostate

Prostate Cancer, Familial, Susceptibility To

Malignant Tumor Of The Prostate

Ngp - New Growth Of Prostate

Tumor Of The Prostate

Prostate Cancer, Hereditary

Cancer Of The Prostate

Malignant Neoplasm Of The Prostate

Prostatic Carcinoma

PC

Prca

Cancer, Prostate

Malignant Prostatic Tumour

Malignant Tumour Of Prostate

Primary Prostate Cancer

Primary Malignant Neoplasm Of Prostate

Prostate Gland Cancer
Non-Syndromic X-Linked Intellectual Disability 21

Mrx21

Mrx34

X-Linked Mental Retardation 21

X-Linked Mental Retardation 34
Ovarian Cancer

Ovarian Carcinoma

Ovarian Neoplasm

Malignant Tumour Of Ovary

Cancer Of The Ovary

Epithelial Ovarian Cancer

Neoplasm Of Ovary

Ovarian Neoplasms

Ovarian Cancers

Malignant Neoplasm Of Ovary

Primary Malignant Neoplasm Of Ovary

Ovarian Cancer, Somatic

Malignant Ovarian Tumor

Ovary Neoplasm

Primary Ovarian Cancer

Tumor Of The Ovary

Malignant Neoplasm Of The Ovary

Malignant Tumor Of The Ovary

Ovarian Malignant Tumor

OC

Ovarian Carcinomas

Cancer, Ovarian

Cancer Of Ovary

Ovary Cancer

Ca Ovary
Breast Cancer

Breast Carcinoma

Male Breast Cancer

Breast Cancer, Familial

Malignant Neoplasm Of Breast

Breast Cancer, Susceptibility To

Breast Cancer, Early-Onset

Malignant Tumor Of Breast

Carcinoma Of Male Breast

Breast Cancer, Invasive Ductal

Breast Cancer, Protection Against

Breast Cancer, Somatic

Breast Cancer, Male

Breast Cancer, Lobular, Somatic

Breast Tumor

Mammary Cancer

Mammary Tumor

Malignant Neoplasm Of Male Breast

Mammary Carcinoma

Male Breast Carcinoma

Familial Cancer Of Breast

Invasive Ductal Breast Carcinoma

Breast Cancer Susceptibility

Breast Cancer, Male, Susceptibility To

Breast Cancer, Early-Onset, Susceptibility To

Malignant Tumor Of The Breast

Mammary Neoplasm

Primary Breast Cancer

Neoplasm Of Male Breast

Carcinoma Of Breast

Breast Cancer In Men

Familial Breast Cancer

Cancer Of Breast

BC

Breast Cancer Familial

Breast Cancer Familial Male

Breast Cancer, Familial Male

Breast Male Carcinoma

Breast Neoplasms

Breast Neoplasms, Male

Mammary Tumors

Mammary Carcinomas

Cancer, Breast

Cancer, Breast, Susceptibility

Invasive Breast Ductal Carcinoma

Breast Neoplasm

Susceptibility To Breast Cancer

Mammary Neoplasms

Animal Mammary Neoplasms

Primary Malignant Neoplasm Of Breast

Infiltrating Ductal Carcinoma Of Breast

Infiltrating Duct Carcinoma Of Unspecified Site

Infiltrating Ductular Carcinoma Of Unspecified Site

Invasive Breast Carcinoma Of No Special Type

Microinvasive Carcinoma Of Breast

Carcinoma With Apocrine Differentiation
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS14928 TPD52 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS14929 TPD52L1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS14930 TPD52L2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta TPD52 VGNC VGNC:84130
Rattus norvegicus TPD52 RGD RGD:1306767
Mus musculus TPD52 MGD MGI:107749