2. Gene
  3. Ripk4 - receptor-interacting serine-threonine kinase 4 Gene

Ripk4 - receptor-interacting serine-threonine kinase 4 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as DIk; PKK; RIP4; ANKK2; Ankrd3; 2310069J12Rik

Gene ID: 72388 | Gene type: protein coding

About Ripk4

Summary

Predicted to enable ATP binding activity and protein serine/threonine kinase activity. Predicted to be involved in morphogenesis of an epithelium and positive regulation of NF-kappaB transcription factor activity. Predicted to act upstream of or within phosphorylation. Located in cytoplasm. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and sensory organ. Used to study popliteal pterygium syndrome. Orthologous to human RIPK4 (receptor interacting serine/threonine kinase 4). [provided by Alliance of Genome Resources, Apr 2022]

Ripk4 Products(1)

mRNA Protein Name
NM_023663.7 NP_076152.2 receptor-interacting serine/threonine-protein kinase 4
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
21903422 MGI
enables protein serine kinase activity IDA
IDA: Inferred from direct assay
28507225 MGI
Biological Process GO Annotation Evidence Reference Source
involved in skin development IMP
IMP: Inferred from mutant phenotype
28507225 MGI
Cellular Component GO Annotation Evidence Reference Source
located in cytoplasm IDA
IDA: Inferred from direct assay
22197488 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

receptor-interacting serine/threonine-protein kinase 4

PKC-associated protein kinase

PKC-regulated protein kinase

ankyrin repeat domain-containing protein 3

Ripk4 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Cross Ripk4 Q9ERK0 TRAF7 Homo sapiens Q6Q0C0
Anti Tag CoIP
21903422
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-148907 CS640 Inhibitor 99.43% Unkown
HY-RS12001 RIPK4 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ripk4 NCBI NCBI:54101