FYTTD1 - forty-two-three domain containing 1 Gene

Homo sapiens

Also known as UIF

Gene ID: 84248 | Gene type: protein coding

About FYTTD1

Cytogenetic location: 3q29 Genomic coordinates (GRCh38): 3:197,749,533-197,787,596 (from NCBI)

This gene has 9 transcripts (splice variants) and 209 orthologues. Ubiquitous expression in testis (RPKM 31.0), esophagus (RPKM 23.1) and 25 other tissues.

Summary

Enables mRNA binding activity. Involved in mRNA export from nucleus. Located in nuclear speck. [provided by Alliance of Genome Resources, Apr 2022]

FYTTD1 Products(2)

mRNA	Protein	Name
NM_001011537.3	NP_001011537.2	UAP56-interacting factor isoform 2
NM_032288.7	NP_115664.2	UAP56-interacting factor isoform 1

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables mRNA binding	IDA IDA: Inferred from direct assay	19836239	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	19836239	GOA

Biological Process GO Annotation	Evidence	Reference	Source
involved in mRNA export from nucleus	IMP IMP: Inferred from mutant phenotype	19836239	GOA

Cellular Component GO Annotation	Evidence	Reference	Source
located in nuclear speck	IDA IDA: Inferred from direct assay	19836239	GOA
located in nucleoplasm	IDA IDA: Inferred from direct assay	19836239	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

FYTTD1 Protein Structure

FYTT

0
100
200
300
318 a.a.

Protein Preferred Names

Protein Names

UAP56-interacting factor

forty-two-three domain-containing protein 1

FYTTD1 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	FYTTD1	Q96QD9	DDX39B	Homo sapiens	Q13838	Anti Tag CoIP	33961781
Intra	FYTTD1	Q96QD9	HNRNPC	Homo sapiens	P07910	Crosslink	30021884
Intra	FYTTD1	Q96QD9	HNRNPC	Homo sapiens	P07910	Anti Tag CoIP	33961781
Cross	FYTTD1	Q96QD9	mta_hhv8p	Human herpesvirus 8	Q2HR75	Imaging	21814512
Cross	FYTTD1	Q96QD9	mta_hhv8p	Human herpesvirus 8	Q2HR75	Pull Down	21814512

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases

Alias

Myasthenic Syndrome, Congenital, 3a, Slow-Channel

Congenital Myasthenic Syndrome 3a	CMS3A
Congenital Myasthenic Syndrome 3a, Slow-Channel	Myasthenic Syndrome, Congenital, Type 3a, Slow-Channel

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS05175	FYTTD1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	FYTTD1	VGNC	VGNC:84178
Rattus norvegicus	FYTTD1	RGD	RGD:1306899
Mus musculus	FYTTD1	MGD	MGI:1917955
Bos taurus	FYTTD1	VGNC	VGNC:29164
Felis catus	FYTTD1	VGNC	VGNC:62401

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