BUD13 - BUD13 homolog Gene

Homo sapiens

Also known as Cwc26; fSAP71

Gene ID: 84811 | Gene type: protein coding

About BUD13

This gene has 3 transcripts (splice variants) and 203 orthologues. Ubiquitous expression in testis (RPKM 10.5), lymph node (RPKM 6.1) and 25 other tissues.

Summary

Enables RNA binding activity. Involved in mRNA splicing, via spliceosome. Located in nucleoplasm. Part of U2-type precatalytic spliceosome. [provided by Alliance of Genome Resources, Apr 2022]

BUD13 Products(2)

mRNA	Protein	Name
NM_001159736.2	NP_001153208.1	BUD13 homolog isoform 2
NM_032725.4	NP_116114.1	BUD13 homolog isoform 1

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	22365833	GOA

Biological Process GO Annotation	Evidence	Reference	Source
involved in mRNA splicing, via spliceosome	IDA IDA: Inferred from direct assay	29360106	GOA

Cellular Component GO Annotation	Evidence	Reference	Source
part of U2-type precatalytic spliceosome	IDA IDA: Inferred from direct assay	29360106	GOA
located in nucleus	IDA IDA: Inferred from direct assay	29360106	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

BUD13 Protein Structure

Bud13

0
100
200
300
400
500
619 a.a.

Protein Preferred Names

Protein Names

BUD13 homolog

functional spliceosome-associated protein 71

BUD13 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	BUD13	Q9BRD0	GPKOW	Homo sapiens	Q92917	Y2H Prey Pooling	25416956
Intra	BUD13	Q9BRD0	GPKOW	Homo sapiens	Q92917	Anti Tag CoIP	22365833
Intra	BUD13	Q9BRD0	GPKOW	Homo sapiens	Q92917	Y2H	22365833
Intra	BUD13	Q9BRD0	GPKOW	Homo sapiens	Q92917	Y2H Array	25416956
Intra	BUD13	Q9BRD0	RBMX2	Homo sapiens	Q9Y388	Y2H	22365833

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases

Alias

Abdominal Obesity-Metabolic Syndrome Quantitative Trait Locus 2

Abdominal Obesity-Metabolic Syndrome	Abdominal Obesity Metabolic Syndrome
Metabolic Syndrome X	Aoms2
Aoms1

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS01684	BUD13 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	BUD13	VGNC	VGNC:38568
Macaca mulatta	BUD13	VGNC	VGNC:82112
Rattus norvegicus	BUD13	RGD	RGD:1308076
Mus musculus	BUD13	MGD	MGI:2443443
Bos taurus	BUD13	VGNC	VGNC:26607
Felis catus	BUD13	VGNC	VGNC:60211

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