RIMBP3 - RIMS binding protein 3 Gene

Homo sapiens

Also known as RIM-BP3; RIMBP3A; RIMBP3.1; RIM-BP3.1; RIM-BP3.A

Gene ID: 85376 | Gene type: protein coding

About RIMBP3

Cytogenetic location: 22q11.21 Genomic coordinates (GRCh38): 22:18,605,815-18,611,919 (from NCBI)

This gene has 1 transcript (splice variant), 80 orthologues and 4 paralogues.

Summary

Predicted to enable benzodiazepine receptor binding activity. Predicted to be involved in fertilization and spermatid development. Predicted to be located in cytoplasm. Predicted to be active in nucleus. Predicted to colocalize with manchette. [provided by Alliance of Genome Resources, Apr 2022]

RIMBP3 Products(1)

mRNA	Protein	Name
NM_015672.2	NP_056487.1	RIMS-binding protein 3A

RIMBP3 Protein Structure

SH3_9

SH3_2

0
300
600
900
1200
1500
1639 a.a.

Protein Preferred Names

Protein Names

RIMS-binding protein 3A

RIMS binding protein 3.1

RIMBP3 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	RIMBP3	Q9UFD9	CTBP2	Homo sapiens	P56545-3	Y2H Prey Pooling	25416956
Intra	RIMBP3	Q9UFD9	CTBP2	Homo sapiens	P56545-3	Y2H Array	25416956
Intra	RIMBP3	Q9UFD9	CREB5	Homo sapiens	Q02930-3	Y2H Prey Pooling	25416956
Intra	RIMBP3	Q9UFD9	CREB5	Homo sapiens	Q02930-3	Validated Y2H	25416956
Intra	RIMBP3	Q9UFD9	PRKAB2	Homo sapiens	O43741	Y2H Prey Pooling	25416956
Intra	RIMBP3	Q9UFD9	POLR1C	Homo sapiens	O15160	Y2H Array	25416956
Intra	RIMBP3	Q9UFD9	PRKAA1	Homo sapiens	Q13131	Validated Y2H	25416956
Intra	RIMBP3	Q9UFD9	FANCL	Homo sapiens	Q9NW38	Y2H Prey Pooling	25416956
Intra	RIMBP3	Q9UFD9	PPIL1	Homo sapiens	Q9Y3C6	Y2H Prey Pooling	25416956
Intra	RIMBP3	Q9UFD9	PPIL1	Homo sapiens	Q9Y3C6	Validated Y2H	25416956
Intra	RIMBP3	Q9UFD9	TLE5	Homo sapiens	Q08117	Y2H Array	25416956
Intra	RIMBP3	Q9UFD9	TLE5	Homo sapiens	Q08117	Y2H Prey Pooling	25416956
Intra	RIMBP3	Q9UFD9	TLE5	Homo sapiens	Q08117	Validated Y2H	25416956
Intra	RIMBP3	Q9UFD9	DTX2	Homo sapiens	Q86UW9	Validated Y2H	25416956
Intra	RIMBP3	Q9UFD9	TRAF3IP2	Homo sapiens	O43734	Validated Y2H	25416956
Intra	RIMBP3	Q9UFD9	TRAF3IP2	Homo sapiens	O43734	Y2H Prey Pooling	25416956
Intra	RIMBP3	Q9UFD9	AQP1	Homo sapiens	P29972	Y2H Array	25416956
Intra	RIMBP3	Q9UFD9	AQP1	Homo sapiens	P29972	Validated Y2H	25416956
Intra	RIMBP3	Q9UFD9	ZNF488	Homo sapiens	Q96MN9	Validated Y2H	25416956
Intra	RIMBP3	Q9UFD9	ZNF488	Homo sapiens	Q96MN9	Y2H Array	25416956
Intra	RIMBP3	Q9UFD9	NOXA1	Homo sapiens	Q86UR1	Y2H Prey Pooling	25416956
Intra	RIMBP3	Q9UFD9	NOXA1	Homo sapiens	Q86UR1	Y2H Array	31515488
Intra	RIMBP3	Q9UFD9	NOXA1	Homo sapiens	Q86UR1	Validated Y2H	25416956

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases

Alias

Anal Carcinoma In Situ

Carcinoma In Situ Of Anal Canal	Carcinoma In Situ Of Anus
Anal Carcinoma Stage 0	Anal Intraepithelial Neoplasia Grade Iii
Intraepithelial Neoplasia Of Anal Canal, High Grade	Ain - [Anal Intraepithelial Neoplasia] High Grade

Martsolf Syndrome 1

Martsolf Syndrome	Cataract-Intellectual Disability-Hypogonadism Syndrome
MARTS1	Marts
Cataract-Mental Retardation-Hypogonadism	Martsolf

Spermatogenic Failure

Azoospermia	Spgf
Spermatogenic Failure, Susceptibility To	Absent Sperm
Aspermatogenesis	Infertility Due To Azoospermia
Hypospermatogenesis	Azoospermatism

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS11977	RIMBP3 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	RIMBP3	MGD	MGI:2685449

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