PAGE1 - PAGE family member 1 Gene

Homo sapiens

Also known as AL5; CT16.3; GAGE-9; GAGEB1; PAGE-1

Gene ID: 8712 | Gene type: protein coding

About PAGE1

Cytogenetic location: Xp11.23 Genomic coordinates (GRCh38): X:49,687,447-49,695,984 (from NCBI)

This gene has 1 transcript (splice variant), 22 orthologues and 22 paralogues. Restricted expression toward testis (RPKM 6.3).

Summary

This gene belongs to a family of genes that are expressed in a variety of tumors but not in normal tissues, except for the testis. Unlike the Other gene family members, this gene does not encode an antigenic peptide. Nothing is presently known about the function of this protein. [provided by RefSeq, Jul 2008]

PAGE1 Products(1)

mRNA	Protein	Name
NM_003785.4	NP_003776.2	P antigen family member 1

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	25416956	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

PAGE1 Protein Structure

GAGE

0
100
146 a.a.

Protein Preferred Names

Protein Names

P antigen family member 1

G antigen 9

PAGE1 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	PAGE1	O75459	PLPP4	Homo sapiens	Q5VZY2	Validated Y2H	32296183
Intra	PAGE1	O75459	TMEM254	Homo sapiens	Q8TBM7	Validated Y2H	32296183
Intra	PAGE1	O75459	CMTM7	Homo sapiens	Q96FZ5	Validated Y2H	32296183
Intra	PAGE1	O75459	SLC2A5	Homo sapiens	P22732	Validated Y2H	32296183
Intra	PAGE1	O75459	TMEM60	Homo sapiens	Q9H2L4	Validated Y2H	32296183
Intra	PAGE1	O75459	TFRC	Homo sapiens	P02786	Validated Y2H	32296183
Intra	PAGE1	O75459	TNF	Homo sapiens	P01375	Validated Y2H	32296183
Intra	PAGE1	O75459	DDX49	Homo sapiens	Q9Y6V7	Y2H Array	32296183
Intra	PAGE1	O75459	DDX49	Homo sapiens	Q9Y6V7	Anti Tag CoIP	33961781
Intra	PAGE1	O75459	DDX49	Homo sapiens	Q9Y6V7	Y2H Prey Pooling	32296183
Intra	PAGE1	O75459	DDX49	Homo sapiens	Q9Y6V7	Validated Y2H	32296183
Intra	PAGE1	O75459	SLC1A1	Homo sapiens	P43005	Validated Y2H	32296183
Intra	PAGE1	O75459	TMEM14B	Homo sapiens	Q9NUH8	Validated Y2H	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-D1590	BODIPY Green 8-P2M		99.21%	Unkown
HY-RS09972	PAGE1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

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