2. Gene
  3. SLC16A7 - solute carrier family 16 member 7 Gene

SLC16A7 - solute carrier family 16 member 7 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as MCT2

Gene ID: 9194 | Gene type: protein coding

About SLC16A7

Cytogenetic location: 12q14.1 Genomic coordinates (GRCh38): 12:59,596,029-59,789,841 (from NCBI)

This gene has 16 transcripts (splice variants), 254 orthologues and 13 paralogues. Broad expression in fat (RPKM 11.7), heart (RPKM 9.2) and 22 other tissues.

Summary

This gene is a member of the Monocarboxylate Transporter family. Members in this family transport metabolites, such as lactate, pyruvate, and ketone bodies. The protein encoded by this gene catalyzes the proton-linked transport of monocarboxylates and has the highest affinity for pyruvate. This protein has been reported to be more highly expressed in prostate and colorectal Cancer specimens when compared to control specimens. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012]

SLC16A7 Products(14)

mRNA Protein Name
XM_017020226.3 XP_016875715.1 monocarboxylate transporter 2 isoform X3
XM_047429885.1 XP_047285841.1 monocarboxylate transporter 2 isoform X3
XM_024449276.2 XP_024305044.1 monocarboxylate transporter 2 isoform X2
NR_073056.2
XM_011538989.3 XP_011537291.1 monocarboxylate transporter 2 isoform X1
XM_011538992.3 XP_011537294.1 monocarboxylate transporter 2 isoform X1
NM_001270622.2 NP_001257551.1 monocarboxylate transporter 2
XM_011538990.4 XP_011537292.1 monocarboxylate transporter 2 isoform X1
NM_001270623.2 NP_001257552.1 monocarboxylate transporter 2
NR_073055.2
XM_011538991.3 XP_011537293.1 monocarboxylate transporter 2 isoform X1
NM_004731.5 NP_004722.2 monocarboxylate transporter 2
XM_011538995.3 XP_011537297.1 monocarboxylate transporter 2 isoform X3
XM_005269231.4 XP_005269288.1 monocarboxylate transporter 2 isoform X2

SLC16A7 Protein Structure

MFS_1

MFS_1: Major Facilitator Superfamily (27 - 390)

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  • 478 a.a.
Protein Preferred Names Protein Names

monocarboxylate transporter 2

solute carrier family 16 (monocarboxylate transporter), member 7

solute carrier family 16, member 7 (monocarboxylic acid transporter 2)

Related Diseases

Diseases Alias
Pharynx Squamous Cell Carcinoma
Colorectal Cancer

Colon Cancer

Colorectal Carcinoma

Colon Carcinoma

Colorectal Cancer, Susceptibility To

Carcinoma Of Colon

CRC

Colorectal Cancer With Chromosomal Instability, Somatic

Colon Cancer, Somatic

Colon Cancer, Susceptibility To

Colonic Neoplasms

Colorectal Neoplasms

Colorectal Cancer, Somatic

Colon Cancer, Advanced, Somatic

Colonic Carcinoma

Colorectal Carcinomas

Colon Cancers

Colorectal Cancers

Cancer, Colorectal, Somatic

Cancer, Colon

Cancer, Colorectal, Susceptibility To

Colorectal Neoplasm

Colonic Neoplasm

Malignant Tumor Of Colon
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS13029 SLC16A7 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS13030 Slc16a7 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS13031 Slc16a7 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris SLC16A7 VGNC VGNC:46245
Felis catus SLC16A7 VGNC VGNC:65214
Bos taurus SLC16A7 VGNC VGNC:34693
Mus musculus SLC16A7 MGD MGI:1330284
Macaca mulatta SLC16A7 VGNC VGNC:77400
Rattus norvegicus SLC16A7 RGD RGD:3691