MTSS1 - MTSS I-BAR domain containing 1 Gene

Homo sapiens

Also known as MIM; MIMA; MIMB

Gene ID: 9788 | Gene type: protein coding

About MTSS1

Cytogenetic location: 8q24.13 Genomic coordinates (GRCh38): 8:124,550,784-124,728,473 (from NCBI)

This gene has 18 transcripts (splice variants), 275 orthologues and 1 paralogue. Ubiquitous expression in liver (RPKM 5.7), adrenal (RPKM 5.6) and 25 other tissues.

Summary

Enables actin monomer binding activity; identical protein binding activity; and signaling receptor binding activity. Predicted to be involved in cellular response to fluid shear stress; negative regulation of epithelial cell proliferation; and urogenital system development. Predicted to act upstream of or within several processes, including actin filament polymerization; adherens junction maintenance; and magnesium ion homeostasis. Located in actin Cytoskeleton. [provided by Alliance of Genome Resources, Apr 2022]

MTSS1 Products(12)

mRNA	Protein	Name
NM_001282971.2	NP_001269900.1	protein MTSS 1 isoform 1
NM_001282974.2	NP_001269903.1	protein MTSS 1 isoform 3
NM_001363294.2	NP_001350223.1	protein MTSS 1 isoform 4
NM_001363295.2	NP_001350224.1	protein MTSS 1 isoform 5
NM_001363296.2	NP_001350225.1	protein MTSS 1 isoform 6
NM_001363297.2	NP_001350226.1	protein MTSS 1 isoform 7
NM_001363298.2	NP_001350227.1	protein MTSS 1 isoform 8
NM_001363299.2	NP_001350228.1	protein MTSS 1 isoform 9
NM_001363300.2	NP_001350229.1	protein MTSS 1 isoform 10
NM_001363301.2	NP_001350230.1	protein MTSS 1 isoform 11
NM_001363302.2	NP_001350231.1	protein MTSS 1 isoform 12
NM_014751.6	NP_055566.3	protein MTSS 1 isoform 2

MTSS1 Protein Structure

IMD

WH2

0
200
400
600
755 a.a.

Protein Preferred Names

Protein Names

protein MTSS 1

MTSS1, I-BAR domain containing

Recombinant MTSS1 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P75930	MTSS1 Protein, Human (His)	EAW92073 (M1-S250)	≥95%

Related Diseases

Diseases

Alias

Oropharyngeal Anthrax

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS08820	MTSS1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	MTSS1	MGD	MGI:2384818
Canis familiaris	MTSS1	VGNC	VGNC:43493
Bos taurus	MTSS1	VGNC	VGNC:31752
Macaca mulatta	MTSS1	VGNC	VGNC:74995
Felis catus	MTSS1	VGNC	VGNC:63660
Rattus norvegicus	MTSS1	RGD	RGD:1309883
Others	MTSS1	NCBI

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