2. Cell Cycle/DNA Damage Antibody-drug Conjugate/ADC Related
  3. Topoisomerase Drug-Linker Conjugates for ADC
  4. GGFG-PAB-Exatecan TFA

GGFG-PAB-Exatecan TFA consists of an ADC toxin Exatecan (HY-13631) and a linker GGFG-PAB, and can be used as a drug-linker conjugate for the synthesis of ADC molecules.

For research use only. We do not sell to patients.

GGFG-PAB-Exatecan TFA Chemical Structure

GGFG-PAB-Exatecan TFA Chemical Structure

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Other Forms of GGFG-PAB-Exatecan TFA:

GGFG-PAB-Exatecan TFA Related Antibodies

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Description

GGFG-PAB-Exatecan TFA consists of an ADC toxin Exatecan (HY-13631) and a linker GGFG-PAB, and can be used as a drug-linker conjugate for the synthesis of ADC molecules[1].

In Vitro

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

GGFG-PAB-Exatecan TFA Related Antibodies
Molecular Weight

1016.95

Formula

C49H48F4N8O12
SMILES

NCC(NCC(N[C@@H](CC1=CC=CC=C1)C(NCC(NC(C=C2)=CC=C2COC(N[C@@H]3C4=C5C(C(N6C5)=CC([C@](O)(C(OC7)=O)CC)=C7C6=O)=NC8=CC(F)=C(C)C(CC3)=C84)=O)=O)=O)=O)=O.OC(C(F)(F)F)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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GGFG-PAB-Exatecan TFA Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

GGFG-PAB-ExatecanTopoisomeraseDrug-Linker Conjugates for ADCCancerInhibitorinhibitorinhibit

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Product Name:
GGFG-PAB-Exatecan TFA
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HY-153069A
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