Glycodeoxycholic acid-d₄

Name: Glycodeoxycholic acid-d 4
Brand: MedChemExpress
SKU: HY-125731S
Rating: 4.5 (1 reviews)

Cat. No.: HY-125731S Purity: 99.52%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Glycodeoxycholic acid-d₄ is the deuterium labeled Glycodeoxycholic Acid. Glycodeoxycholic Acid is an endogenous metabolite.

For research use only. We do not sell to patients.

Glycodeoxycholic acid-d<sub>4</sub> Chemical Structure

Glycodeoxycholic acid-d₄ Chemical Structure

CAS No. : 1069132-37-1

Size	Price	Stock	Quantity
1 mg	USD 120	In-stock	Estimated Time of Arrival: December 31
5 mg		Get quote
10 mg		Get quote

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Based on 1 publication(s) in Google Scholar

Other Forms of Glycodeoxycholic acid-d₄:

Glycodeoxycholic Acid In-stock

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Biological Activity
Purity & Documentation
References
Customer Review

Description

Glycodeoxycholic acid-d₄ is the deuterium labeled Glycodeoxycholic Acid. Glycodeoxycholic Acid is an endogenous metabolite.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

453.65

Formula

C₂₆H₃₉D₄NO₅

CAS No.

1069132-37-1

Unlabeled CAS

360-65-6

Appearance

Solid

Color

White to off-white

SMILES

C[C@@]12[C@](CC[C@]2([H])[C@H](C)CCC(NCC(O)=O)=O)([H])[C@@]3([H])[C@@](C[C@@H]1O)([H])[C@@]4([C@](C([2H])([2H])[C@@H](C([2H])([2H])C4)O)([H])CC3)C

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility

In Vitro:

DMSO : 125 mg/mL (275.54 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.2043 mL	11.0217 mL	22.0434 mL
5 mM	0.4409 mL	2.2043 mL	4.4087 mL
10 mM	0.2204 mL	1.1022 mL	2.2043 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.52%

Select Batch:

Data Sheet (271 KB) SDS (251 KB)

COA (250 KB) HNMR (148 KB) RP-HPLC (141 KB) MS (140 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO / DMSO	1 mM	2.2043 mL	11.0217 mL	22.0434 mL	55.1086 mL
	5 mM	0.4409 mL	2.2043 mL	4.4087 mL	11.0217 mL
	10 mM	0.2204 mL	1.1022 mL	2.2043 mL	5.5109 mL
	15 mM	0.1470 mL	0.7348 mL	1.4696 mL	3.6739 mL
	20 mM	0.1102 mL	0.5511 mL	1.1022 mL	2.7554 mL
	25 mM	0.0882 mL	0.4409 mL	0.8817 mL	2.2043 mL
	30 mM	0.0735 mL	0.3674 mL	0.7348 mL	1.8370 mL
	40 mM	0.0551 mL	0.2755 mL	0.5511 mL	1.3777 mL
	50 mM	0.0441 mL	0.2204 mL	0.4409 mL	1.1022 mL
	60 mM	0.0367 mL	0.1837 mL	0.3674 mL	0.9185 mL
	80 mM	0.0276 mL	0.1378 mL	0.2755 mL	0.6889 mL
	100 mM	0.0220 mL	0.1102 mL	0.2204 mL	0.5511 mL