GnRH antagonist 2

Cat. No.: HY-134864 Purity: 98.05%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

GnRH antagonist 2 (formula I) is a GnRH receptor antagonist that can be used for endometriosis research.

For research use only. We do not sell to patients.

GnRH antagonist 2 Chemical Structure

CAS No. : 1709823-61-9

Size	Price	Stock	Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	USD 601	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	USD 601	In-stock	Estimated Time of Arrival: December 31
Solid
5 mg	USD 450	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 720	In-stock	Estimated Time of Arrival: December 31
25 mg	USD 1450	In-stock	Estimated Time of Arrival: December 31
50 mg	USD 2350	In-stock	Estimated Time of Arrival: December 31
100 mg	USD 3800	In-stock	Estimated Time of Arrival: December 31
200 mg		Get quote
500 mg		Get quote

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Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
References
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Description

GnRH antagonist 2 (formula I) is a GnRH receptor antagonist that can be used for endometriosis research^[1].

Molecular Weight

607.57

Formula

C₂₈H₂₇F₂N₉O₅

CAS No.

1709823-61-9

Appearance

Solid

Color

White to yellow

SMILES

O=C(NOC)NC1=CC=C(N2N=C(C(C(N3C4=NN=C(OC)C=C4)=O)=C2CN(C)C)N(CC5=C(F)C=CC=C5F)C3=O)C=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 150 mg/mL (246.89 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.6459 mL	8.2295 mL	16.4590 mL
5 mM	0.3292 mL	1.6459 mL	3.2918 mL
10 mM	0.1646 mL	0.8230 mL	1.6459 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 98.58%

Select Batch:

Data Sheet (268 KB) SDS (251 KB)

COA (251 KB) LCMS (93 KB)

Handling Instructions (2659 KB)

References

[1]. Quanliang Zhang, et al. Crystalline form of gnrh receptor antagonist and preparation method therefor. WO2018086608A1.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	1.6459 mL	8.2295 mL	16.4590 mL	41.1475 mL
	5 mM	0.3292 mL	1.6459 mL	3.2918 mL	8.2295 mL
	10 mM	0.1646 mL	0.8230 mL	1.6459 mL	4.1148 mL
	15 mM	0.1097 mL	0.5486 mL	1.0973 mL	2.7432 mL
	20 mM	0.0823 mL	0.4115 mL	0.8230 mL	2.0574 mL
	25 mM	0.0658 mL	0.3292 mL	0.6584 mL	1.6459 mL
	30 mM	0.0549 mL	0.2743 mL	0.5486 mL	1.3716 mL
	40 mM	0.0411 mL	0.2057 mL	0.4115 mL	1.0287 mL
	50 mM	0.0329 mL	0.1646 mL	0.3292 mL	0.8230 mL
	60 mM	0.0274 mL	0.1372 mL	0.2743 mL	0.6858 mL
	80 mM	0.0206 mL	0.1029 mL	0.2057 mL	0.5143 mL
	100 mM	0.0165 mL	0.0823 mL	0.1646 mL	0.4115 mL