1. Immunology/Inflammation
  2. Interleukin Related
  3. Goflikicept

Goflikicept  (Synonyms: RPH 104)

Cat. No.: HY-P99645 Purity: 98.32%
Data Sheet Technical Support

Goflikicept (RPH 104) is a fusion protein that selectively binds and inactivates both circulating IL-1β and IL-1α. Goflikicept has the potential for the research of ST-segment elevation myocardial infarction (STEMI).

For research use only. We do not sell to patients.

CAS No. : 2416984-26-2

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Description

Goflikicept (RPH 104) is a fusion protein that selectively binds and inactivates both circulating IL-1β and IL-1α. Goflikicept has the potential for the research of ST-segment elevation myocardial infarction (STEMI)[1].

Species

Human

In Vitro

Goflikicept is a heterodimeric fusion protein that blocks the IL-1 signaling pathway (estimated by the reduced level of hsCRP), and reduces inflammatory response[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Goflikicept reduces myocardial damage and improves cardiac remodeling, and can be used in research of IL-1 activity associated diseases, such as acute myocardial infarction and heart failure[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

126.22 kDa

CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Goflikicept]

Shipping

Shipping with dry ice.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Format
  • IL1RAP (interleukin-1 receptor accessory protein)fragment 21-358-IGHG1 Fc (Fragment constant)-covalent dimer-IL1R1 (type 1 interleukin-1 receptor, interleukin 1 receptor, type I)fragment 21-333-IGHG1 Fc (Fragment constant)
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Goflikicept
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HY-P99645
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