GSK-3β inhibitor 12

Cat. No.: HY-148133 Purity: 99.81%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

GSK-3β inhibitor 12 (compound 15) is an inhibitor of GSK-3β. GSK-3β inhibitor 12 inhibits 49.11% and 37.11% activity of 25 μM and 50 μM GSK-3β, respectively. GSK-3β inhibitor 12 can be used for the research of neurodegenerative diseases.

For research use only. We do not sell to patients.

GSK-3β inhibitor 12 Chemical Structure

CAS No. : 784170-07-6

Size	Price	Stock	Quantity
5 mg	USD 200	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 320	In-stock	Estimated Time of Arrival: December 31
25 mg	USD 550	In-stock	Estimated Time of Arrival: December 31
50 mg	USD 785	In-stock	Estimated Time of Arrival: December 31
100 mg		Get quote
200 mg		Get quote

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Customer Review

Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
References
Customer Review

Description

Molecular Weight

271.34

Formula

C₁₄H₁₃N₃OS

CAS No.

784170-07-6

Appearance

Solid

Color

Light brown to brown

SMILES

O=C(CC1=CNC2=C1C=CC=C2)NC3=NC=C(C)S3

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 125 mg/mL (460.68 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.6854 mL	18.4271 mL	36.8541 mL
5 mM	0.7371 mL	3.6854 mL	7.3708 mL
10 mM	0.3685 mL	1.8427 mL	3.6854 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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μL

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.81%

Select Batch:

Data Sheet (271 KB) SDS (393 KB)

COA (251 KB) HNMR (255 KB) LCMS (92 KB)

Handling Instructions (2659 KB)

References

[1]. Martinez Gil A, et al. N-(2-Thiazolyl)-amide derivatives as GSK-3 inhibitors. EP20060380099. 2007

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	3.6854 mL	18.4271 mL	36.8541 mL	92.1353 mL
	5 mM	0.7371 mL	3.6854 mL	7.3708 mL	18.4271 mL
	10 mM	0.3685 mL	1.8427 mL	3.6854 mL	9.2135 mL
	15 mM	0.2457 mL	1.2285 mL	2.4569 mL	6.1424 mL
	20 mM	0.1843 mL	0.9214 mL	1.8427 mL	4.6068 mL
	25 mM	0.1474 mL	0.7371 mL	1.4742 mL	3.6854 mL
	30 mM	0.1228 mL	0.6142 mL	1.2285 mL	3.0712 mL
	40 mM	0.0921 mL	0.4607 mL	0.9214 mL	2.3034 mL
	50 mM	0.0737 mL	0.3685 mL	0.7371 mL	1.8427 mL
	60 mM	0.0614 mL	0.3071 mL	0.6142 mL	1.5356 mL
	80 mM	0.0461 mL	0.2303 mL	0.4607 mL	1.1517 mL
	100 mM	0.0369 mL	0.1843 mL	0.3685 mL	0.9214 mL