H-Trp-NH2.HCl

Name: H-Trp-NH2.HCl
Brand: MedChemExpress
SKU: HY-W008766
Rating: 4.5 (1 reviews)

Cat. No.: HY-W008766 Purity: 97.08%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

H-Trp-NH2.HCl is an endogenous metabolite.

For research use only. We do not sell to patients.

H-Trp-NH2.HCl Chemical Structure

CAS No. : 5022-65-1

Size	Price	Stock	Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	USD 33	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	USD 33	In-stock	Estimated Time of Arrival: December 31
Solid
1 g	USD 30	In-stock	Estimated Time of Arrival: December 31
5 g		Get quote
10 g		Get quote

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Based on 1 publication(s) in Google Scholar

Other Forms of H-Trp-NH2.HCl:

L-Tryptophanamide Get quote

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Description

H-Trp-NH2.HCl is an endogenous metabolite.

Molecular Weight

239.70

Formula

C₁₁H₁₄ClN₃O

CAS No.

5022-65-1

Appearance

Solid

Color

White to off-white

SMILES

N[C@@](C(N)=O)([H])CC1=CNC2=CC=CC=C12.Cl

Structure Classification

Others

Initial Source

Endogenous metabolite

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (417.19 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H₂O : 100 mg/mL (417.19 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	4.1719 mL	20.8594 mL	41.7188 mL
5 mM	0.8344 mL	4.1719 mL	8.3438 mL
10 mM	0.4172 mL	2.0859 mL	4.1719 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 2.5 mg/mL (10.43 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Protocol 2

Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 2.5 mg/mL (10.43 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
Protocol 3

Add each solvent one by one: 10% DMSO 90% Corn Oil
Solubility: ≥ 2.5 mg/mL (10.43 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown). If the continuous dosing period exceeds half a month, please choose this protocol carefully.
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL Corn oil, and mix evenly.

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 97.08%

Select Batch:

Data Sheet (248 KB) SDS (393 KB)

COA (255 KB) HNMR (125 KB) RP-HPLC (272 KB)

Handling Instructions (2659 KB)

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO / H₂O	1 mM	4.1719 mL	20.8594 mL	41.7188 mL	104.2970 mL
	5 mM	0.8344 mL	4.1719 mL	8.3438 mL	20.8594 mL
	10 mM	0.4172 mL	2.0859 mL	4.1719 mL	10.4297 mL
	15 mM	0.2781 mL	1.3906 mL	2.7813 mL	6.9531 mL
	20 mM	0.2086 mL	1.0430 mL	2.0859 mL	5.2149 mL
	25 mM	0.1669 mL	0.8344 mL	1.6688 mL	4.1719 mL
	30 mM	0.1391 mL	0.6953 mL	1.3906 mL	3.4766 mL
	40 mM	0.1043 mL	0.5215 mL	1.0430 mL	2.6074 mL
	50 mM	0.0834 mL	0.4172 mL	0.8344 mL	2.0859 mL
	60 mM	0.0695 mL	0.3477 mL	0.6953 mL	1.7383 mL
	80 mM	0.0521 mL	0.2607 mL	0.5215 mL	1.3037 mL
	100 mM	0.0417 mL	0.2086 mL	0.4172 mL	1.0430 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

H-Trp-NH2.HCl Related Classifications

Metabolic Disease

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

H-Trp-NH2.HCl5022-65-1Endogenous MetaboliteInhibitorinhibitorinhibit

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H-Trp-NH2.HCl

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Other Forms of H-Trp-NH2.HCl:

H-Trp-NH2.HCl Related Antibodies

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Complete Stock Solution Preparation Table

H-Trp-NH2.HCl Related Classifications

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