1. Metabolic Enzyme/Protease Neuronal Signaling
  2. Endogenous Metabolite Cholinesterase (ChE)
  3. His-D-beta-Nal-Ala-Trp-D-Phe-Lys-NH2 TFA

His-D-beta-Nal-Ala-Trp-D-Phe-Lys-NH2 TFA 

Cat. No.: HY-P5189A Purity: 99.56%
SDS COA Handling Instructions

His-D-beta-Nal-Ala-Trp-D-Phe-Lys-NH2 TFA, is a growth hormone releasing peptide, as well as a metabolite of GHRP-1. GHRP-1, or Ala-His-D-beta Nal-Ala-Trp-D-Phe-Lys-NH2, has the effect of promoting the release of growth hormone (GH). GHRP-1 increases GH release and increases [Ca2+]i levels in static monolayer cells of rat pituitary gland, but does not affect cAMP levels.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

His-D-beta-Nal-Ala-Trp-D-Phe-Lys-NH2 TFA Chemical Structure

His-D-beta-Nal-Ala-Trp-D-Phe-Lys-NH2 TFA Chemical Structure

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Description

His-D-beta-Nal-Ala-Trp-D-Phe-Lys-NH2 TFA, is a growth hormone releasing peptide, as well as a metabolite of GHRP-1. GHRP-1, or Ala-His-D-beta Nal-Ala-Trp-D-Phe-Lys-NH2, has the effect of promoting the release of growth hormone (GH). GHRP-1 increases GH release and increases [Ca2+]i levels in static monolayer cells of rat pituitary gland, but does not affect cAMP levels[1].

Molecular Weight

998.06

Formula

C50H58F3N11O8

Appearance

Solid

Color

White to off-white

Sequence

H-{D-beta-Nal}-AW-{D-Phe}-K-NH2

Sequence Shortening

His-{D-beta-Nal}-Ala-Trp-{D-Phe}-Lys-NH2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture and light, under nitrogen

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (100.19 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.0019 mL 5.0097 mL 10.0194 mL
5 mM 0.2004 mL 1.0019 mL 2.0039 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.56%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.0019 mL 5.0097 mL 10.0194 mL 25.0486 mL
5 mM 0.2004 mL 1.0019 mL 2.0039 mL 5.0097 mL
10 mM 0.1002 mL 0.5010 mL 1.0019 mL 2.5049 mL
15 mM 0.0668 mL 0.3340 mL 0.6680 mL 1.6699 mL
20 mM 0.0501 mL 0.2505 mL 0.5010 mL 1.2524 mL
25 mM 0.0401 mL 0.2004 mL 0.4008 mL 1.0019 mL
30 mM 0.0334 mL 0.1670 mL 0.3340 mL 0.8350 mL
40 mM 0.0250 mL 0.1252 mL 0.2505 mL 0.6262 mL
50 mM 0.0200 mL 0.1002 mL 0.2004 mL 0.5010 mL
60 mM 0.0167 mL 0.0835 mL 0.1670 mL 0.4175 mL
80 mM 0.0125 mL 0.0626 mL 0.1252 mL 0.3131 mL
100 mM 0.0100 mL 0.0501 mL 0.1002 mL 0.2505 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
His-D-beta-Nal-Ala-Trp-D-Phe-Lys-NH2 TFA
Cat. No.:
HY-P5189A
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