Homo Sildenafil

Cat. No.: HY-131100 Purity: 99.32%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Homo Sildenafil, an analog of Sildenafil, acts as a phosphodiesterase inhibitor.

For research use only. We do not sell to patients.

Homo Sildenafil Chemical Structure

CAS No. : 642928-07-2

Size	Price	Stock	Quantity
5 mg	USD 95	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 170	In-stock	Estimated Time of Arrival: December 31
25 mg	USD 360	In-stock	Estimated Time of Arrival: December 31
50 mg	USD 610	In-stock	Estimated Time of Arrival: December 31
100 mg	USD 976	In-stock	Estimated Time of Arrival: December 31
200 mg		Get quote
500 mg		Get quote

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Other Forms of Homo Sildenafil:

Homo Sildenafil-d₅ Get quote
Homo Sildenafil (Standard) Get quote

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Biological Activity
Purity & Documentation
References
Customer Review

Description

Homo Sildenafil, an analog of Sildenafil, acts as a phosphodiesterase inhibitor^[1].

Molecular Weight

488.60

Formula

C₂₃H₃₂N₆O₄S

CAS No.

642928-07-2

Appearance

Solid

Color

White to off-white

SMILES

O=C1C(N(C)N=C2CCC)=C2N=C(C3=CC(S(=O)(N4CCN(CC)CC4)=O)=CC=C3OCC)N1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 50 mg/mL (102.33 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.0467 mL	10.2333 mL	20.4666 mL
5 mM	0.4093 mL	2.0467 mL	4.0933 mL
10 mM	0.2047 mL	1.0233 mL	2.0467 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.32%

Select Batch:

Data Sheet (269 KB) SDS (393 KB)

COA (250 KB) HNMR (281 KB) LCMS (94 KB)

Handling Instructions (2659 KB)

References

[1]. Jackie D Corbin, et al. Vardenafil: Structural Basis for Higher Potency Over Sildenafil in Inhibiting cGMP-specific phosphodiesterase-5 (PDE5). Neurochem Int. 2004 Nov;45(6):859-63. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.0467 mL	10.2333 mL	20.4666 mL	51.1666 mL
	5 mM	0.4093 mL	2.0467 mL	4.0933 mL	10.2333 mL
	10 mM	0.2047 mL	1.0233 mL	2.0467 mL	5.1167 mL
	15 mM	0.1364 mL	0.6822 mL	1.3644 mL	3.4111 mL
	20 mM	0.1023 mL	0.5117 mL	1.0233 mL	2.5583 mL
	25 mM	0.0819 mL	0.4093 mL	0.8187 mL	2.0467 mL
	30 mM	0.0682 mL	0.3411 mL	0.6822 mL	1.7056 mL
	40 mM	0.0512 mL	0.2558 mL	0.5117 mL	1.2792 mL
	50 mM	0.0409 mL	0.2047 mL	0.4093 mL	1.0233 mL
	60 mM	0.0341 mL	0.1706 mL	0.3411 mL	0.8528 mL
	80 mM	0.0256 mL	0.1279 mL	0.2558 mL	0.6396 mL
	100 mM	0.0205 mL	0.1023 mL	0.2047 mL	0.5117 mL

Homo Sildenafil Related Classifications

Endocrinology

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Homo Sildenafil642928-07-2Phosphodiesterase (PDE)Inhibitorinhibitorinhibit

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