2. Apoptosis Metabolic Enzyme/Protease NF-κB Immunology/Inflammation
  3. Apoptosis Indoleamine 2,3-Dioxygenase (IDO) Reactive Oxygen Species
  4. IDOi-Pt(IV) prodrug-1

IDOi-Pt(IV) prodrug-1 (Compound 10) is an IDOi-Pt(IV) prodrug. IDOi-Pt(IV) prodrug-1 inhibits IDO expression. IDOi-Pt(IV) prodrug-1 induces apoptosis, decreases the mitochondrial membrane potential, inhibits tumor cell migration and invasion. IDOi-Pt(IV) prodrug-1 induces reactive oxygen species-mediated endoplasmic reticulum stress and secretion of damage-associated molecular patterns (DAMPs), thereby presenting immunogenic cell death (ICD) effects. IDOi-Pt(IV) prodrug-1 has high-efficiency and low-toxicity antitumor effects compared to Cisplatin (HY-17394).

For research use only. We do not sell to patients.

IDOi-Pt(IV) prodrug-1 Chemical Structure

IDOi-Pt(IV) prodrug-1 Chemical Structure

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IDOi-Pt(IV) prodrug-1 Related Antibodies

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Description

IDOi-Pt(IV) prodrug-1 (Compound 10) is an IDOi-Pt(IV) prodrug. IDOi-Pt(IV) prodrug-1 inhibits IDO expression. IDOi-Pt(IV) prodrug-1 induces apoptosis, decreases the mitochondrial membrane potential, inhibits tumor cell migration and invasion. IDOi-Pt(IV) prodrug-1 induces reactive oxygen species-mediated endoplasmic reticulum stress and secretion of damage-associated molecular patterns (DAMPs), thereby presenting immunogenic cell death (ICD) effects. IDOi-Pt(IV) prodrug-1 has high-efficiency and low-toxicity antitumor effects compared to Cisplatin (HY-17394)[1].

Molecular Weight

749.96

Formula

C21H26Cl3N3O6PtS
SMILES

[NH3][Pt](Cl)(Cl)(O)([NH3])OC(CCCC(N1C2=CC=C(C=C2C(SC3=CC(OC)=CC(OC)=C3)=C1)Cl)=O)=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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IDOi-Pt(IV) prodrug-1 Related Classifications

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Keywords:

IDOi-Pt(IV) prodrug-1ApoptosisIndoleamine 2,3-Dioxygenase (IDO)Reactive Oxygen SpeciesInhibitorinhibitorinhibit

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