2. Apoptosis
  3. Apoptosis
  4. Kp7-6

Kp7-6, a Fas mimetic peptide, is a Fas/FasL antagonist. Kp7-6 protects cells from Fas-mediated apoptosis, and protects mice from Fas-mediated hepatic injury.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Kp7-6 Chemical Structure

Kp7-6 Chemical Structure

CAS No. : 629628-53-1

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1 mg USD 55 In-stock
5 mg USD 120 In-stock
10 mg USD 190 In-stock
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Based on 1 publication(s) in Google Scholar

Kp7-6 Related Antibodies

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Description

Kp7-6, a Fas mimetic peptide, is a Fas/FasL antagonist. Kp7-6 protects cells from Fas-mediated apoptosis, and protects mice from Fas-mediated hepatic injury[1][2].

Molecular Weight

1077.15

Formula

C48H56N10O15S2
CAS No.
Appearance

Solid

Color

White to off-white

Sequence

Tyr-Cys-Asp-Glu-His-Phe-Cys-Tyr (Disulfide bridge:Cys2-Cys7)
Sequence Shortening

YCDEHFCY (Disulfide bridge:Cys2-Cys7)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (92.84 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.9284 mL 4.6419 mL 9.2838 mL
5 mM 0.1857 mL 0.9284 mL 1.8568 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.77%

COA (261 KB) LCMS (94 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.9284 mL 4.6419 mL 9.2838 mL 23.2094 mL
5 mM 0.1857 mL 0.9284 mL 1.8568 mL 4.6419 mL
10 mM 0.0928 mL 0.4642 mL 0.9284 mL 2.3209 mL
15 mM 0.0619 mL 0.3095 mL 0.6189 mL 1.5473 mL
20 mM 0.0464 mL 0.2321 mL 0.4642 mL 1.1605 mL
25 mM 0.0371 mL 0.1857 mL 0.3714 mL 0.9284 mL
30 mM 0.0309 mL 0.1547 mL 0.3095 mL 0.7736 mL
40 mM 0.0232 mL 0.1160 mL 0.2321 mL 0.5802 mL
50 mM 0.0186 mL 0.0928 mL 0.1857 mL 0.4642 mL
60 mM 0.0155 mL 0.0774 mL 0.1547 mL 0.3868 mL
80 mM 0.0116 mL 0.0580 mL 0.1160 mL 0.2901 mL
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Kp7-6 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Kp7-6629628-53-1ApoptosisFashepatic injuryInhibitorinhibitorinhibit

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