2. MAPK/ERK Pathway Stem Cell/Wnt GPCR/G Protein
  3. ERK Ras
  4. KRAS G12C inhibitor 61

KRAS G12C inhibitor 61 (Example 3) inhibits phospho-ERK 1/2 in MIA PaCa-2 cells with an IC50 value of 9 nM. KRAS G12C inhibitor 61 can be used for research of pancreatic, colorectal, and lung cancers.

For research use only. We do not sell to patients.

KRAS G12C inhibitor 61 Chemical Structure

KRAS G12C inhibitor 61 Chemical Structure

CAS No. : 2300967-40-0

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KRAS G12C inhibitor 61 Related Antibodies

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ERK ERK1 ERK2 ERK5 ERK8

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K-Ras H-Ras N-Ras Ras

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Description

KRAS G12C inhibitor 61 (Example 3) inhibits phospho-ERK 1/2 in MIA PaCa-2 cells with an IC50 value of 9 nM. KRAS G12C inhibitor 61 can be used for research of pancreatic, colorectal, and lung cancers[1].

IC50 & Target

K-Ras WT

 

Molecular Weight

590.09

Formula

C31H33ClFN7O2
CAS No.
SMILES

O=C1N=C(N2[C@@H](C)CN([C@H](C)C2)C(C=C)=O)C3=C(N1C4=C(C)C=CN=C4C(C)C)N=C(C5=C(N)C=CC=C5F)C(Cl)=C3
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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KRAS G12C inhibitor 61 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

KRAS G12C inhibitor 612300967-40-0ERKRasExtracellular signal regulated kinasespancreaticcolorectallung cancerKRAS G12Cphospho-ERKPaCa-2Inhibitorinhibitorinhibit

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