2. Metabolic Enzyme/Protease
  3. Phosphatase
  4. L-690330 hydrate

L-690330 hydrate is a competitive inhibitor of inositol monophosphatase (IMPase) with Kis of 0.27 and 0.19 μM for recombinant human and bovine IMPase, 0.30 and 0.42 μM for human and bovine frontal cortex IMPase, respectively. L-690330 hydrate exhibits 10-fold more sensitive than mouse and rat IMPase.

For research use only. We do not sell to patients.

L-690330 hydrate Chemical Structure

L-690330 hydrate Chemical Structure

CAS No. : 2930564-26-2

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 USD 330 In-stock
Solution
10 mM * 1 mL in DMSO USD 330 In-stock
Solid
5 mg USD 300 In-stock
10 mg USD 480 In-stock
50 mg   Get quote  
100 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

Other Forms of L-690330 hydrate:

L-690330 hydrate Related Antibodies

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Description

L-690330 hydrate is a competitive inhibitor of inositol monophosphatase (IMPase) with Kis of 0.27 and 0.19 μM for recombinant human and bovine IMPase, 0.30 and 0.42 μM for human and bovine frontal cortex IMPase, respectively. L-690330 hydrate exhibits 10-fold more sensitive than mouse and rat IMPase[1].

In Vitro

L-690330 hydrate (50 μM; 1 hour) induces P-AMPK and autophagy and increases LC3-I/II and p-AMPK expression in HEK293 cells[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

L-690330 hydrate Related Antibodies
In Vivo

L-690330 hydrate (intracerebroventricular?injection; 0.1 μmol) has no effects on their motor activity and coordination in the beam walking, except a reduction in time spent in light in the dark/light test[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Eight-week-old male ICR mice[3]
Dosage: 0.1 μmol
Administration: Intracerebroventricular injection
Result: Did not effect mice well-being by i.c.v injection.
Molecular Weight

316.14

Formula

C8H14O9P2
CAS No.
Appearance

Solid

Color

Off-white to light yellow

SMILES

OC1=CC=C(OC(P(O)(O)=O)(P(O)(O)=O)C)C=C1.O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 31 mg/mL (98.06 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H2O : 31 mg/mL (98.06 mM; Need ultrasonic and warming)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.1632 mL 15.8158 mL 31.6316 mL
5 mM 0.6326 mL 3.1632 mL 6.3263 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

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C2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: ≥98.0%

COA (248 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / H2O 1 mM 3.1632 mL 15.8158 mL 31.6316 mL 79.0789 mL
5 mM 0.6326 mL 3.1632 mL 6.3263 mL 15.8158 mL
10 mM 0.3163 mL 1.5816 mL 3.1632 mL 7.9079 mL
15 mM 0.2109 mL 1.0544 mL 2.1088 mL 5.2719 mL
20 mM 0.1582 mL 0.7908 mL 1.5816 mL 3.9539 mL
25 mM 0.1265 mL 0.6326 mL 1.2653 mL 3.1632 mL
30 mM 0.1054 mL 0.5272 mL 1.0544 mL 2.6360 mL
40 mM 0.0791 mL 0.3954 mL 0.7908 mL 1.9770 mL
50 mM 0.0633 mL 0.3163 mL 0.6326 mL 1.5816 mL
60 mM 0.0527 mL 0.2636 mL 0.5272 mL 1.3180 mL
80 mM 0.0395 mL 0.1977 mL 0.3954 mL 0.9885 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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L-690330 hydrate Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

L-6903302930564-26-2L690330L 690330PhosphataseLSDsensitivityimmobilitybehaviorInhibitorinhibitorinhibit

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