2. Metabolic Enzyme/Protease
  3. Lactate Dehydrogenase
  4. LDHA-IN-4

AZ-33 is a selective lactate dehydrogenase A (LDHA) inhibitor with an IC50 of 0.5 μM and a Kd of 0.093 μM.

For research use only. We do not sell to patients.

LDHA-IN-4 Chemical Structure

LDHA-IN-4 Chemical Structure

CAS No. : 1370290-34-8

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5 mg USD 120 In-stock
10 mg USD 200 In-stock
25 mg USD 390 In-stock
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Based on 1 publication(s) in Google Scholar

LDHA-IN-4 Related Antibodies

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Description

AZ-33 is a selective lactate dehydrogenase A (LDHA) inhibitor with an IC50 of 0.5 μM and a Kd of 0.093 μM[1].

Molecular Weight

497.56

Formula

C25H27N3O6S
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(C(CC1=CC=C(CCCC(NCCC(NC2=CC3=C(N=C(C)S3)C=C2)=O)=O)C=C1)C(O)=O)O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (200.98 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.0098 mL 10.0490 mL 20.0981 mL
5 mM 0.4020 mL 2.0098 mL 4.0196 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.0098 mL 10.0490 mL 20.0981 mL 50.2452 mL
5 mM 0.4020 mL 2.0098 mL 4.0196 mL 10.0490 mL
10 mM 0.2010 mL 1.0049 mL 2.0098 mL 5.0245 mL
15 mM 0.1340 mL 0.6699 mL 1.3399 mL 3.3497 mL
20 mM 0.1005 mL 0.5025 mL 1.0049 mL 2.5123 mL
25 mM 0.0804 mL 0.4020 mL 0.8039 mL 2.0098 mL
30 mM 0.0670 mL 0.3350 mL 0.6699 mL 1.6748 mL
40 mM 0.0502 mL 0.2512 mL 0.5025 mL 1.2561 mL
50 mM 0.0402 mL 0.2010 mL 0.4020 mL 1.0049 mL
60 mM 0.0335 mL 0.1675 mL 0.3350 mL 0.8374 mL
80 mM 0.0251 mL 0.1256 mL 0.2512 mL 0.6281 mL
100 mM 0.0201 mL 0.1005 mL 0.2010 mL 0.5025 mL
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LDHA-IN-4 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

LDHA-IN-41370290-34-8Lactate DehydrogenaseLDHInhibitorinhibitorinhibit

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