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  3. Lithocholic acid 3-sulfate-d4 disodium

Lithocholic acid 3-sulfate-d4 disodium  (Synonyms: Sulfolithocholic acid-d4 (disodium))

Cat. No.: HY-113238AS Purity: 99.68%
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Lithocholic acid 3-sulfate-d4 (disodium) is the deuterium labeled Lithocholic acid 3-sulfate disodium[1].

For research use only. We do not sell to patients.

Lithocholic acid 3-sulfate-d<sub>4</sub> disodium Chemical Structure

Lithocholic acid 3-sulfate-d4 disodium Chemical Structure

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Based on 1 publication(s) in Google Scholar

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Description

Lithocholic acid 3-sulfate-d4 (disodium) is the deuterium labeled Lithocholic acid 3-sulfate disodium[1].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

504.62

Formula

C24H34D4Na2O6S

Unlabeled CAS
Appearance

Solid

Color

White to off-white

SMILES

O=C(CC[C@@H](C)[C@H]1CCC2[C@]1(C)CCC3C2CC[C@]([H])(C([2H])([C@@H](C([2H])(C4)[2H])OS(=O)(O[Na])=O)[2H])[C@@]34C)O[Na]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (198.17 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.9817 mL 9.9084 mL 19.8169 mL
5 mM 0.3963 mL 1.9817 mL 3.9634 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration
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Volume
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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.9817 mL 9.9084 mL 19.8169 mL 49.5422 mL
5 mM 0.3963 mL 1.9817 mL 3.9634 mL 9.9084 mL
10 mM 0.1982 mL 0.9908 mL 1.9817 mL 4.9542 mL
15 mM 0.1321 mL 0.6606 mL 1.3211 mL 3.3028 mL
20 mM 0.0991 mL 0.4954 mL 0.9908 mL 2.4771 mL
25 mM 0.0793 mL 0.3963 mL 0.7927 mL 1.9817 mL
30 mM 0.0661 mL 0.3303 mL 0.6606 mL 1.6514 mL
40 mM 0.0495 mL 0.2477 mL 0.4954 mL 1.2386 mL
50 mM 0.0396 mL 0.1982 mL 0.3963 mL 0.9908 mL
60 mM 0.0330 mL 0.1651 mL 0.3303 mL 0.8257 mL
80 mM 0.0248 mL 0.1239 mL 0.2477 mL 0.6193 mL
100 mM 0.0198 mL 0.0991 mL 0.1982 mL 0.4954 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Lithocholic acid 3-sulfate-d4 disodium
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HY-113238AS
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