Methyl 2-(1H-indol-3-yl)acetate

Name: Methyl 2-(1H-indol-3-yl)acetate
Brand: MedChemExpress
SKU: HY-W015224
Rating: 4.5 (1 reviews)

Cat. No.: HY-W015224 Purity: 99.12%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Methyl 2-(1H-indol-3-yl)acetate is an endogenous metabolite.

For research use only. We do not sell to patients.

Methyl 2-(1H-indol-3-yl)acetate Chemical Structure

CAS No. : 1912-33-0

Size	Price	Stock	Quantity
Solid or liquid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	USD 55	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	USD 55	In-stock	Estimated Time of Arrival: December 31
Solid or liquid
100 mg	USD 30	In-stock	Estimated Time of Arrival: December 31
200 mg		Get quote
500 mg		Get quote

or Bulk Inquiry

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Methyl 2-(1H-indol-3-yl)acetate:

Methyl 2-(1H-indol-3-yl)acetate-d₅ Get quote

Featured Recommendations

•Related Screening Libraries:

•Related Small Molecules:

•Related Proteins:

Biological Activity
Purity & Documentation
Customer Review

Description

Methyl 2-(1H-indol-3-yl)acetate is an endogenous metabolite.

IC₅₀ & Target

Microbial Metabolite

Human Endogenous Metabolite

Molecular Weight

189.21

Formula

C₁₁H₁₁NO₂

CAS No.

1912-33-0

Appearance

<50°C Solid,>52°C Liquid

Color

Brown to black

SMILES

COC(=O)CC1=CNC2=C1C=CC=C2

Structure Classification

Others

Initial Source

Endogenous metabolite

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Pure form	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 50 mg/mL (264.26 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	5.2851 mL	26.4257 mL	52.8513 mL
5 mM	1.0570 mL	5.2851 mL	10.5703 mL
10 mM	0.5285 mL	2.6426 mL	5.2851 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 2.5 mg/mL (13.21 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Please enter your animal formula composition:

DMSO +

Tween-80 +

Saline

Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.

The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).

Calculation results:

Working solution concentration: mg/mL

Method for preparing stock solution: mg drug dissolved in μL DMSO (Stock solution concentration: mg/mL).

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only. If necessary, please contact MedChemExpress (MCE).

Method for preparing in vivo working solution for animal experiments: Take μL DMSO stock solution, add μL . μL , mix evenly, next add μL Tween 80, mix evenly, then add μL Saline.

If the continuous dosing period exceeds half a month, please choose this protocol carefully.

Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.

Purity & Documentation

Purity: 99.12%

Select Batch:

Data Sheet (267 KB) SDS (393 KB)

COA (252 KB) HNMR (118 KB) RP-HPLC (207 KB)

Handling Instructions (2659 KB)

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	5.2851 mL	26.4257 mL	52.8513 mL	132.1283 mL
	5 mM	1.0570 mL	5.2851 mL	10.5703 mL	26.4257 mL
	10 mM	0.5285 mL	2.6426 mL	5.2851 mL	13.2128 mL
	15 mM	0.3523 mL	1.7617 mL	3.5234 mL	8.8086 mL
	20 mM	0.2643 mL	1.3213 mL	2.6426 mL	6.6064 mL
	25 mM	0.2114 mL	1.0570 mL	2.1141 mL	5.2851 mL
	30 mM	0.1762 mL	0.8809 mL	1.7617 mL	4.4043 mL
	40 mM	0.1321 mL	0.6606 mL	1.3213 mL	3.3032 mL
	50 mM	0.1057 mL	0.5285 mL	1.0570 mL	2.6426 mL
	60 mM	0.0881 mL	0.4404 mL	0.8809 mL	2.2021 mL
	80 mM	0.0661 mL	0.3303 mL	0.6606 mL	1.6516 mL
	100 mM	0.0529 mL	0.2643 mL	0.5285 mL	1.3213 mL