1. Immunology/Inflammation NF-κB Metabolic Enzyme/Protease
  2. Reactive Oxygen Species
  3. Methyl aminolevulinate

Methyl aminolevulinate is an agent used as a sensitizer in photodynamic therapy (PDT). Methyl aminolevulinate is a proagent that can be metabolized to Protoporphyrin IX.

At equivalent molar concentrations, both the salt and free forms of a compound exhibit comparable biological activity. Nevertheless, the salt form (Methyl aminolevulinate hydrochloride) usually boasts enhanced water solubility and stability.

For research use only. We do not sell to patients.

Methyl aminolevulinate Chemical Structure

Methyl aminolevulinate Chemical Structure

CAS No. : 33320-16-0

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Description

Methyl aminolevulinate is an agent used as a sensitizer in photodynamic therapy (PDT). Methyl aminolevulinate is a proagent that can be metabolized to Protoporphyrin IX[1].

Cellular Effect
Cell Line Type Value Description References
HeLa IC50
763 μM
Compound: 5-ALA-OMe
Photosensitization activity against human HeLa cells assessed as reduction in cell viability incubated for 4 hrs followed by LED light array irradiation followed by further incubation for 24 hrs by MTT assay
Photosensitization activity against human HeLa cells assessed as reduction in cell viability incubated for 4 hrs followed by LED light array irradiation followed by further incubation for 24 hrs by MTT assay
[PMID: 31398615]
Clinical Trial
Molecular Weight

145.16

Formula

C6H11NO3

CAS No.
SMILES

O=C(OC)CCC(CN)=O

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Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Methyl aminolevulinate
Cat. No.:
HY-A0169
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