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  3. Tetrazine
  4. Methyltetrazine-Amine

Methyltetrazine-Amine, a tetrazine compound, is used for the site-specific dual functionalization of the resulting bioconjugates.

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Methyltetrazine-Amine Chemical Structure

Methyltetrazine-Amine Chemical Structure

CAS No. : 1345955-28-3

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Based on 1 publication(s) in Google Scholar

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Methyltetrazine-Amine Related Antibodies

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Description

Methyltetrazine-Amine, a tetrazine compound, is used for the site-specific dual functionalization of the resulting bioconjugates[1].

Molecular Weight

201.23

Formula

C10H11N5
CAS No.
Appearance

Solid

Color

Purple to purplish red

SMILES

NCC1=CC=C(C2=NN=C(C)N=N2)C=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 20.83 mg/mL (103.51 mM; ultrasonic and warming and adjust pH to 2 with HCl and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.9694 mL 24.8472 mL 49.6944 mL
5 mM 0.9939 mL 4.9694 mL 9.9389 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 98.02%

COA (245 KB) HNMR (234 KB) RP-HPLC (228 KB) LCMS (88 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 4.9694 mL 24.8472 mL 49.6944 mL 124.2360 mL
5 mM 0.9939 mL 4.9694 mL 9.9389 mL 24.8472 mL
10 mM 0.4969 mL 2.4847 mL 4.9694 mL 12.4236 mL
15 mM 0.3313 mL 1.6565 mL 3.3130 mL 8.2824 mL
20 mM 0.2485 mL 1.2424 mL 2.4847 mL 6.2118 mL
25 mM 0.1988 mL 0.9939 mL 1.9878 mL 4.9694 mL
30 mM 0.1656 mL 0.8282 mL 1.6565 mL 4.1412 mL
40 mM 0.1242 mL 0.6212 mL 1.2424 mL 3.1059 mL
50 mM 0.0994 mL 0.4969 mL 0.9939 mL 2.4847 mL
60 mM 0.0828 mL 0.4141 mL 0.8282 mL 2.0706 mL
80 mM 0.0621 mL 0.3106 mL 0.6212 mL 1.5529 mL
100 mM 0.0497 mL 0.2485 mL 0.4969 mL 1.2424 mL
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Methyltetrazine-Amine Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Methyltetrazine-Amine1345955-28-3OtherstetrazinedualfunctionalizationbispecificsInhibitorinhibitorinhibit

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