N,S-Bis-Fmoc-Glutathione TFA

Cat. No.: HY-P4277A Purity: 97.06%: FAQs
Data Sheet SDS COA Handling Instructions Technical Support

N,S-Bis-Fmoc-Glutathione TFA is a potent glyoxalase II inhibitor with a K_i value of 0.75 μM and an IC₅₀ of 2.5 μM.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

N,S-Bis-Fmoc-Glutathione TFA Chemical Structure

Size	Stock	Quantity
25 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	In-stock	Estimated Time of Arrival: December 31
100 mg	Get quote
200 mg	Get quote

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This product is a controlled substance and not for sale in your territory.

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Based on 1 publication(s) in Google Scholar

Other Forms of N,S-Bis-Fmoc-Glutathione TFA:

N,S-Bis-Fmoc-Glutathione Get quote

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Biological Activity
Purity & Documentation
References
Customer Review

Description

N,S-Bis-Fmoc-Glutathione TFA is a potent glyoxalase II inhibitor with a K_i value of 0.75 μM and an IC₅₀ of 2.5 μM^[1].

Molecular Weight

865.82

Formula

C₄₂H₃₈F₃N₃O₁₂S

Appearance

Solid

Sequence

{Fmoc}-{γ-Glu(({Cys-Fmoc})-Gly)}

Sequence Shortening

{Fmoc}-{γ-Glu(({Cys-Fmoc})-Gly)}

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Powder	-80°C	2 years
	-20°C	1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

DMSO : 50 mg/mL (57.75 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.1550 mL	5.7749 mL	11.5497 mL
5 mM	0.2310 mL	1.1550 mL	2.3099 mL
10 mM	0.1155 mL	0.5775 mL	1.1550 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 97.06%

Select Batch:

Data Sheet (271 KB) SDS (252 KB)

COA (252 KB) LCMS (101 KB)

Handling Instructions (2659 KB)

References

[1]. Norton SJ, et al. Inhibitors and inhibition studies of mammalian glyoxalase II activity. Biochem Soc Trans. 1993 May;21(2):545-9. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	1.1550 mL	5.7749 mL	11.5497 mL	28.8744 mL
	5 mM	0.2310 mL	1.1550 mL	2.3099 mL	5.7749 mL
	10 mM	0.1155 mL	0.5775 mL	1.1550 mL	2.8874 mL
	15 mM	0.0770 mL	0.3850 mL	0.7700 mL	1.9250 mL
	20 mM	0.0577 mL	0.2887 mL	0.5775 mL	1.4437 mL
	25 mM	0.0462 mL	0.2310 mL	0.4620 mL	1.1550 mL
	30 mM	0.0385 mL	0.1925 mL	0.3850 mL	0.9625 mL
	40 mM	0.0289 mL	0.1444 mL	0.2887 mL	0.7219 mL
	50 mM	0.0231 mL	0.1155 mL	0.2310 mL	0.5775 mL