N,S-Bis-Fmoc-Glutathione

Cat. No.: HY-P4277 Purity: 99.89%: FAQs
Data Sheet
SDS

COA
Handling Instructions Technical Support

N,S-Bis-Fmoc-Glutathione is a potent glyoxalase II inhibitor with a K_i value of 0.75 μM and an IC₅₀ of 2.5 μM.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

N,S-Bis-Fmoc-Glutathione Chemical Structure

CAS No. : 149438-56-2

Size	Stock	Quantity
25 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	In-stock	Estimated Time of Arrival: December 31
100 mg	Get quote
200 mg	Get quote

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This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of N,S-Bis-Fmoc-Glutathione:

N,S-Bis-Fmoc-Glutathione TFA Get quote

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Biological Activity
Purity & Documentation
References
Customer Review

Description

N,S-Bis-Fmoc-Glutathione is a potent glyoxalase II inhibitor with a K_i value of 0.75 μM and an IC₅₀ of 2.5 μM^[1].

Molecular Weight

751.80

Formula

C₄₀H₃₇N₃O₁₀S

CAS No.

149438-56-2

Appearance

Solid

Color

White to off-white

Sequence

{Fmoc}-{γ-Glu(({Cys-Fmoc})-Gly)}

Sequence Shortening

{Fmoc}-{γ-Glu(({Cys-Fmoc})-Gly)}

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Powder	-80°C	2 years
	-20°C	1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

DMSO : 125 mg/mL (166.27 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.3301 mL	6.6507 mL	13.3014 mL
5 mM	0.2660 mL	1.3301 mL	2.6603 mL
10 mM	0.1330 mL	0.6651 mL	1.3301 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.89%

Select Batch:

Data Sheet (272 KB) SDS (252 KB)

COA (250 KB) HNMR (299 KB) RP-HPLC (247 KB) LCMS (94 KB)

Handling Instructions (2659 KB)

References

[1]. Norton SJ, et al. Inhibitors and inhibition studies of mammalian glyoxalase II activity. Biochem Soc Trans. 1993 May;21(2):545-9. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	1.3301 mL	6.6507 mL	13.3014 mL	33.2535 mL
	5 mM	0.2660 mL	1.3301 mL	2.6603 mL	6.6507 mL
	10 mM	0.1330 mL	0.6651 mL	1.3301 mL	3.3254 mL
	15 mM	0.0887 mL	0.4434 mL	0.8868 mL	2.2169 mL
	20 mM	0.0665 mL	0.3325 mL	0.6651 mL	1.6627 mL
	25 mM	0.0532 mL	0.2660 mL	0.5321 mL	1.3301 mL
	30 mM	0.0443 mL	0.2217 mL	0.4434 mL	1.1085 mL
	40 mM	0.0333 mL	0.1663 mL	0.3325 mL	0.8313 mL
	50 mM	0.0266 mL	0.1330 mL	0.2660 mL	0.6651 mL
	60 mM	0.0222 mL	0.1108 mL	0.2217 mL	0.5542 mL
	80 mM	0.0166 mL	0.0831 mL	0.1663 mL	0.4157 mL
	100 mM	0.0133 mL	0.0665 mL	0.1330 mL	0.3325 mL