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  4. N1,N11-Diethylnorspermine tetrahydrochloride

N1,N11-Diethylnorspermine tetrahydrochloride  (Synonyms: DENSPM tetrahydrochloride; BENSPM tetrahydrochloride)

Cat. No.: HY-13610A Purity: ≥98.0%
COA Handling Instructions

Molarity Calculator

N1,N11-Diethylnorspermine tetrahydrochloride (DENSPM tetrahydrochloride) potently induces SSAT (spermidine/spermine N1-acetyltransferase) mRNA and effectively stabilizes SSAT enzyme activity.

For research use only. We do not sell to patients.

N1,N11-Diethylnorspermine tetrahydrochloride Chemical Structure

N1,N11-Diethylnorspermine tetrahydrochloride Chemical Structure

CAS No. : 156886-85-0

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in Water
ready for reconstitution
 USD 143 In-stock
Solution
10 mM * 1 mL in Water USD 143 In-stock
Solid
5 mg USD 130 In-stock
10 mg USD 210 In-stock
25 mg USD 420 In-stock
50 mg USD 680 In-stock
100 mg USD 1100 In-stock
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Based on 2 publication(s) in Google Scholar

Other Forms of N1,N11-Diethylnorspermine tetrahydrochloride:

N1,N11-Diethylnorspermine tetrahydrochloride Related Antibodies

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  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

N1,N11-Diethylnorspermine tetrahydrochloride (DENSPM tetrahydrochloride) potently induces SSAT (spermidine/spermine N1-acetyltransferase) mRNA and effectively stabilizes SSAT enzyme activity[1].

Molecular Weight

390.26

Formula

C13H36Cl4N4
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

CCNCCCNCCCNCCCNCC.[H]Cl.[H]Cl.[H]Cl.[H]Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (256.24 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.5624 mL 12.8120 mL 25.6239 mL
5 mM 0.5125 mL 2.5624 mL 5.1248 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  PBS

    Solubility: 100 mg/mL (256.24 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: ≥98.0%

COA (241 KB) HNMR (117 KB) MS (98 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 2.5624 mL 12.8120 mL 25.6239 mL 64.0599 mL
5 mM 0.5125 mL 2.5624 mL 5.1248 mL 12.8120 mL
10 mM 0.2562 mL 1.2812 mL 2.5624 mL 6.4060 mL
15 mM 0.1708 mL 0.8541 mL 1.7083 mL 4.2707 mL
20 mM 0.1281 mL 0.6406 mL 1.2812 mL 3.2030 mL
25 mM 0.1025 mL 0.5125 mL 1.0250 mL 2.5624 mL
30 mM 0.0854 mL 0.4271 mL 0.8541 mL 2.1353 mL
40 mM 0.0641 mL 0.3203 mL 0.6406 mL 1.6015 mL
50 mM 0.0512 mL 0.2562 mL 0.5125 mL 1.2812 mL
60 mM 0.0427 mL 0.2135 mL 0.4271 mL 1.0677 mL
80 mM 0.0320 mL 0.1601 mL 0.3203 mL 0.8007 mL
100 mM 0.0256 mL 0.1281 mL 0.2562 mL 0.6406 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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N1,N11-Diethylnorspermine tetrahydrochloride Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

N1,N11-Diethylnorspermine tetrahydrochloride156886-85-0DENSPM tetrahydrochlorideBENSPM tetrahydrochlorideOthersInhibitorinhibitorinhibit

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