NH2-Gly-PAB-Exatecan-D-glucuronic acid formic

Cat. No.: HY-160885A Purity: 99.34%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

NH2-Gly-PAB-Exatecan-D-glucuronic acid formic (Compound 8) is the formic salt form of H2N-Gly-PAB-Exatecan-D-glucuronic acid. H2N-Gly-PAB-Exatecan-D-glucuronic acid formic is an intermediate, which reacts with NHS group to form drug-linker conjugate for ADC, Mal-Gly-PAB-Exatecan-D-glucuronic acid (HY-153179).

For research use only. We do not sell to patients.

NH2-Gly-PAB-Exatecan-D-glucuronic acid formic Chemical Structure

Size	Price	Stock	Quantity
1 mg	USD 200	In-stock	Estimated Time of Arrival: December 31
5 mg	USD 500	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 800	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

or Bulk Inquiry

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of NH2-Gly-PAB-Exatecan-D-glucuronic acid formic:

NH2-Gly-PAB-Exatecan-D-glucuronic acid Get quote

Featured Recommendations

•Related Screening Libraries:

•Related Small Molecules:

•Related Proteins:

View All ADC Cytotoxin Isoform Specific Products:

View All Isoforms

Auristatin Calicheamicins Camptothecins Daunorubicins/Doxorubicins Duocarmycins Maytansinoids Pyrrolobenzodiazepines Traditional Cytotoxic Agents

Biological Activity
Purity & Documentation
References
Customer Review

Description

Molecular Weight

879.79

Formula

C₄₁H₄₂FN₅O₁₆

Appearance

Solid

Color

White to light yellow

SMILES

NCC(NC(C=C1COC(N[C@@H]2C3=C4C(C(N5C4)=CC([C@](O)(C(OC6)=O)CC)=C6C5=O)=NC7=CC(F)=C(C)C(CC2)=C73)=O)=C(C=C1)O[C@@H]8O[C@@H]([C@H]([C@@H]([C@H]8O)O)O)C(O)=O)=O.OC=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

DMSO : 50 mg/mL (56.83 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.1366 mL	5.6832 mL	11.3663 mL
5 mM	0.2273 mL	1.1366 mL	2.2733 mL
10 mM	0.1137 mL	0.5683 mL	1.1366 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.34%

Select Batch:

Data Sheet (277 KB) SDS (252 KB)

COA (265 KB) HNMR (268 KB) RP-HPLC (268 KB) LCMS (101 KB)

Handling Instructions (2659 KB)

References

[1]. DICKGIESSER S, et al., Methods and tools for conjugation to antibodies. WO2023170239.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	1.1366 mL	5.6832 mL	11.3663 mL	28.4159 mL
	5 mM	0.2273 mL	1.1366 mL	2.2733 mL	5.6832 mL
	10 mM	0.1137 mL	0.5683 mL	1.1366 mL	2.8416 mL
	15 mM	0.0758 mL	0.3789 mL	0.7578 mL	1.8944 mL
	20 mM	0.0568 mL	0.2842 mL	0.5683 mL	1.4208 mL
	25 mM	0.0455 mL	0.2273 mL	0.4547 mL	1.1366 mL
	30 mM	0.0379 mL	0.1894 mL	0.3789 mL	0.9472 mL
	40 mM	0.0284 mL	0.1421 mL	0.2842 mL	0.7104 mL
	50 mM	0.0227 mL	0.1137 mL	0.2273 mL	0.5683 mL