2. Epigenetics
  3. Histone Methyltransferase
  4. NSD-IN-2

NSD-IN-2 (compound 151) is a potent and irreversible NSD1 inhibitor. NSD-IN-2 can be used in research of cancer.

For research use only. We do not sell to patients.

NSD-IN-2 Chemical Structure

NSD-IN-2 Chemical Structure

CAS No. : 2351225-46-0

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NSD-IN-2 Related Antibodies

Top Publications Citing Use of Products

View All Histone Methyltransferase Isoform Specific Products:

View All Isoforms
EZH1 EZH2 DOT1L SMYD2 SMYD3 SUV39H2/KMT1B EHMT2/G9a/KMT1C EHMT1/GLP/KMT1D SETDB1/KMT2G SETD2/KMT3A NSD2/MMSET/WHSC1 SETD7/KMT7 SETD8/KMT5A PRMT1 PRMT3 PRMT4 PRMT5 PRMT6 PRMT7 PRMT8

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Description

NSD-IN-2 (compound 151) is a potent and irreversible NSD1 inhibitor. NSD-IN-2 can be used in research of cancer[1].

Cellular Effect
Cell Line Type Value Description References
Bone marrow cell GI50
0.9 μM
Compound: 119
Anticancer activity against BALB/c mouse bone marrow cells expressing NUP98-NSD1 assessed as cell growth inhibition incubated for 7 days by MTT assay
Anticancer activity against BALB/c mouse bone marrow cells expressing NUP98-NSD1 assessed as cell growth inhibition incubated for 7 days by MTT assay
[PMID: 34591474]
Molecular Weight

221.28

Formula

C10H11N3OS
CAS No.
SMILES

OC1=C2N=C(N)SC2=CC(N3C(C)C3)=C1
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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NSD-IN-2 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

NSD-IN-22351225-46-0Histone MethyltransferaseInhibitorinhibitorinhibit

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