2. Metabolic Enzyme/Protease
  3. Phosphodiesterase (PDE)
  4. PDE10-IN-5

PDE10-IN-5 is a phosphodiesterase 10 (PDE 10) inhibitor, can be used for researching certain central nervous system (CNS) disorders.

For research use only. We do not sell to patients.

PDE10-IN-5 Chemical Structure

PDE10-IN-5 Chemical Structure

CAS No. : 898562-99-7

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 USD 405 In-stock
Solution
10 mM * 1 mL in DMSO USD 405 In-stock
Solid
1 mg USD 160 In-stock
5 mg USD 400 In-stock
10 mg USD 650 In-stock
25 mg USD 1300 In-stock
50 mg USD 2000 In-stock
100 mg USD 3300 In-stock
200 mg   Get quote  
500 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

PDE10-IN-5 Related Antibodies

Top Publications Citing Use of Products

View All Phosphodiesterase (PDE) Isoform Specific Products:

View All Isoforms
PDE1 PDE2 PDE3 PDE4 PDE5 PDE6 PDE7 PDE9 PDE10 PDE11 PDE12 PDE8 Autotaxin

  • Biological Activity

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Description

PDE10-IN-5 is a phosphodiesterase 10 (PDE 10) inhibitor, can be used for researching certain central nervous system (CNS) disorders[1].

Molecular Weight

460.45

Formula

C26H19F3N4O
CAS No.
Appearance

Solid

Color

Off-white to light yellow

SMILES

FC(F)(CN1N=CC(C2=CC=NC=C2)=C1C3=CC=C(OCC4=NC5=C(C=C4)C=CC=C5)C=C3)F
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 31.25 mg/mL (67.87 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.1718 mL 10.8589 mL 21.7179 mL
5 mM 0.4344 mL 2.1718 mL 4.3436 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.1718 mL 10.8589 mL 21.7179 mL 54.2947 mL
5 mM 0.4344 mL 2.1718 mL 4.3436 mL 10.8589 mL
10 mM 0.2172 mL 1.0859 mL 2.1718 mL 5.4295 mL
15 mM 0.1448 mL 0.7239 mL 1.4479 mL 3.6196 mL
20 mM 0.1086 mL 0.5429 mL 1.0859 mL 2.7147 mL
25 mM 0.0869 mL 0.4344 mL 0.8687 mL 2.1718 mL
30 mM 0.0724 mL 0.3620 mL 0.7239 mL 1.8098 mL
40 mM 0.0543 mL 0.2715 mL 0.5429 mL 1.3574 mL
50 mM 0.0434 mL 0.2172 mL 0.4344 mL 1.0859 mL
60 mM 0.0362 mL 0.1810 mL 0.3620 mL 0.9049 mL
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PDE10-IN-5 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PDE10-IN-5898562-99-7Phosphodiesterase (PDE)central nervous systemInhibitorinhibitorinhibit

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