Penconazole-d₇

Cat. No.: HY-135761S Purity: 99.17%: FAQs
Data Sheet SDS COA Handling Instructions

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Penconazole-d₇ is the deuterium labeled Penconazole[1]. Penconazole is a typical triazole fungicide, and mainly applied on apples, grapes, and vegetables to control powdery mildew. Penconazole inhibits sterol biosynthesis in fungi. Penconazole decrease AChE activity in the cerebrum and cerebellum of rats[2][3].

For research use only. We do not sell to patients.

Penconazole-d<sub>7</sub> Chemical Structure

Penconazole-d₇ Chemical Structure

CAS No. : 1628110-84-8

Size	Price	Stock	Quantity
1 mg	USD 135	In-stock	Estimated Time of Arrival: December 31
5 mg		Get quote
10 mg		Get quote

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Other Forms of Penconazole-d₇:

Penconazole Get quote

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Purity & Documentation
References
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Description

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

291.23

Formula

C₁₃H₈D₇Cl₂N₃

CAS No.

1628110-84-8

Unlabeled CAS

66246-88-6

Appearance

Solid

Color

White to off-white

SMILES

[2H]C([2H])([2H])C([2H])([2H])C([2H])([2H])C(C1=C(C=C(C=C1)Cl)Cl)CN2C=NC=N2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (343.37 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.4337 mL	17.1686 mL	34.3371 mL
5 mM	0.6867 mL	3.4337 mL	6.8674 mL
10 mM	0.3434 mL	1.7169 mL	3.4337 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

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μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.17%

Select Batch:

Data Sheet (277 KB) SDS (252 KB)

COA (254 KB) HNMR (827 KB) RP-HPLC (822 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]

[2]. Husak VV, et al. Acute exposure to the penconazole-containing fungicide Topas partially augments antioxidant potential in goldfish tissues. Comp Biochem Physiol C Toxicol Pharmacol. 2017;193:1-8. [Content Brief]

[3]. Chaâbane M, et al. Penconazole alters redox status, cholinergic function, and membrane-bound ATPases in the cerebrum and cerebellum of adult rats. Hum Exp Toxicol. 201736(8):854-866. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	3.4337 mL	17.1686 mL	34.3371 mL	85.8428 mL
	5 mM	0.6867 mL	3.4337 mL	6.8674 mL	17.1686 mL
	10 mM	0.3434 mL	1.7169 mL	3.4337 mL	8.5843 mL
	15 mM	0.2289 mL	1.1446 mL	2.2891 mL	5.7229 mL
	20 mM	0.1717 mL	0.8584 mL	1.7169 mL	4.2921 mL
	25 mM	0.1373 mL	0.6867 mL	1.3735 mL	3.4337 mL
	30 mM	0.1145 mL	0.5723 mL	1.1446 mL	2.8614 mL
	40 mM	0.0858 mL	0.4292 mL	0.8584 mL	2.1461 mL
	50 mM	0.0687 mL	0.3434 mL	0.6867 mL	1.7169 mL
	60 mM	0.0572 mL	0.2861 mL	0.5723 mL	1.4307 mL
	80 mM	0.0429 mL	0.2146 mL	0.4292 mL	1.0730 mL
	100 mM	0.0343 mL	0.1717 mL	0.3434 mL	0.8584 mL