2. Metabolic Enzyme/Protease
  3. Phosphatase
  4. PGAM1-IN-1

PGAM1-IN-1 is a phosphoglycerate mutase 1 (PGAM1) inhibitor with an IC50 of 6.4 μM.

For research use only. We do not sell to patients.

PGAM1-IN-1 Chemical Structure

PGAM1-IN-1 Chemical Structure

CAS No. : 2438637-65-9

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 USD 385 In-stock
Solution
10 mM * 1 mL in DMSO USD 385 In-stock
Solid
5 mg USD 350 In-stock
10 mg USD 550 In-stock
50 mg USD 1650 In-stock
100 mg   Get quote  
200 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

PGAM1-IN-1 Related Antibodies

Top Publications Citing Use of Products

1 Publications Citing Use of MCE PGAM1-IN-1

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

PGAM1-IN-1 is a phosphoglycerate mutase 1 (PGAM1) inhibitor with an IC50 of 6.4 μM[1].

IC50 & Target

IC50: 6.4 μM (PGAM1)[1]
In Vitro

PGAM1-IN-1 (Compound 9h) inhibits H1299 proliferation with an IC50 of 14.1±1.9 μM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

PGAM1-IN-1 Related Antibodies
Molecular Weight

435.81

Formula

C19H11ClFNO6S
CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

O=C1C2=C(O)C=C(NS(C3=C(F)C(Cl)=CC=C3)(=O)=O)C=C2OC4=C1C(O)=CC=C4
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 5 mg/mL (11.47 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.2946 mL 11.4729 mL 22.9458 mL
5 mM 0.4589 mL 2.2946 mL 4.5892 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.2946 mL 11.4729 mL 22.9458 mL 57.3644 mL
5 mM 0.4589 mL 2.2946 mL 4.5892 mL 11.4729 mL
10 mM 0.2295 mL 1.1473 mL 2.2946 mL 5.7364 mL
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PGAM1-IN-1 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PGAM1-IN-12438637-65-9PhosphataseInhibitorinhibitorinhibit

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Cat. No.:
HY-128681
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