Phenylacetylglutamine-d₅ (Synonyms: NSC 203800-d₅; Phenylacetyl-L-glutamine-d₅)

Name: Phenylacetylglutamine-d 5
Brand: MedChemExpress
SKU: HY-W050026S
Rating: 5.0 (2 reviews)

Cat. No.: HY-W050026S Purity: 98.18%: FAQs
Data Sheet SDS COA Handling Instructions

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Phenylacetylglutamine-d₅ is the deuterium labeled Phenylacetylglutamine. Phenylacetylglutamine is a colonic microbial metabolite from amino acid fermentation[1].

For research use only. We do not sell to patients.

Phenylacetylglutamine-d<sub>5</sub> Chemical Structure

Phenylacetylglutamine-d₅ Chemical Structure

CAS No. : 1331909-01-3

Size	Price	Stock	Quantity
1 mg	USD 288	In-stock	Estimated Time of Arrival: December 31
5 mg	USD 634	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 888	In-stock	Estimated Time of Arrival: December 31
25 mg	USD 1600	In-stock	Estimated Time of Arrival: December 31
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100 mg		Get quote

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Based on 2 publication(s) in Google Scholar

Other Forms of Phenylacetylglutamine-d₅:

Phenylacetylglutamine In-stock

2 Publications Citing Use of MCE Phenylacetylglutamine-d₅

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Description

Phenylacetylglutamine-d₅ is the deuterium labeled Phenylacetylglutamine. Phenylacetylglutamine is a colonic microbial metabolite from amino acid fermentation[1].

Molecular Weight

269.31

Formula

C₁₃H₁₁D₅N₂O₄

CAS No.

1331909-01-3

Unlabeled CAS

28047-15-6

Appearance

Solid

Color

White to off-white

SMILES

O=C(N[C@@H](CCC(N)=O)C(O)=O)CC1=C([2H])C([2H])=C([2H])C([2H])=C1[2H]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : ≥ 50 mg/mL (185.66 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.7132 mL	18.5660 mL	37.1319 mL
5 mM	0.7426 mL	3.7132 mL	7.4264 mL
10 mM	0.3713 mL	1.8566 mL	3.7132 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 1.25 mg/mL (4.64 mM); Clear solution

This protocol yields a clear solution of ≥ 1.25 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (12.5 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Protocol 2

Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 1.25 mg/mL (4.64 mM); Clear solution

This protocol yields a clear solution of ≥ 1.25 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (12.5 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
Protocol 3

Add each solvent one by one: 10% DMSO 90% Corn Oil
Solubility: ≥ 1.25 mg/mL (4.64 mM); Clear solution

This protocol yields a clear solution of ≥ 1.25 mg/mL (saturation unknown). If the continuous dosing period exceeds half a month, please choose this protocol carefully.
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (12.5 mg/mL) to 900 μL Corn oil, and mix evenly.

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Please enter your animal formula composition:

DMSO +

Tween-80 +

Saline

Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.

The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).

Calculation results:

Working solution concentration: mg/mL

Method for preparing stock solution: mg drug dissolved in μL DMSO (Stock solution concentration: mg/mL).

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only. If necessary, please contact MedChemExpress (MCE).

Method for preparing in vivo working solution for animal experiments: Take μL DMSO stock solution, add μL . μL , mix evenly, next add μL Tween 80, mix evenly, then add μL Saline.

If the continuous dosing period exceeds half a month, please choose this protocol carefully.

Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.

Purity & Documentation

Purity: 98.18%

Select Batch:

Data Sheet (273 KB) SDS (252 KB)

COA (249 KB) HNMR (639 KB) RP-HPLC (881 KB)

Handling Instructions (2659 KB)

References

[1]. Poesen R, et al. Microbiota-Derived Phenylacetylglutamine Associates with Overall Mortality and Cardiovascular Disease in Patients with CKD. J Am Soc Nephrol. 2016 Nov;27(11):3479-3487. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	3.7132 mL	18.5660 mL	37.1319 mL	92.8298 mL
	5 mM	0.7426 mL	3.7132 mL	7.4264 mL	18.5660 mL
	10 mM	0.3713 mL	1.8566 mL	3.7132 mL	9.2830 mL
	15 mM	0.2475 mL	1.2377 mL	2.4755 mL	6.1887 mL
	20 mM	0.1857 mL	0.9283 mL	1.8566 mL	4.6415 mL
	25 mM	0.1485 mL	0.7426 mL	1.4853 mL	3.7132 mL
	30 mM	0.1238 mL	0.6189 mL	1.2377 mL	3.0943 mL
	40 mM	0.0928 mL	0.4641 mL	0.9283 mL	2.3207 mL
	50 mM	0.0743 mL	0.3713 mL	0.7426 mL	1.8566 mL
	60 mM	0.0619 mL	0.3094 mL	0.6189 mL	1.5472 mL
	80 mM	0.0464 mL	0.2321 mL	0.4641 mL	1.1604 mL
	100 mM	0.0371 mL	0.1857 mL	0.3713 mL	0.9283 mL

Phenylacetylglutamine-d₅ Related Classifications

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Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Phenylacetylglutamine-d₅1331909-01-3NSC 203800-d₅Phenylacetyl-L-glutamine-d₅Endogenous MetaboliteIsotope-Labeled CompoundsdeuteratedformPhenylacetylglutaminemicrobialmetaboliteaminoacidfermentationInhibitorinhibitorinhibit

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Phenylacetylglutamine-d5 (Synonyms: NSC 203800-d5; Phenylacetyl-L-glutamine-d5)

Customer Review

Other Forms of Phenylacetylglutamine-d5:

Phenylacetylglutamine-d5 Related Antibodies

2 Publications Citing Use of MCE Phenylacetylglutamine-d5

Featured Recommendations

•Related Small Molecules:

•Related Proteins:

Biological Activity

Purity & Documentation

References

Customer Review

Molarity Calculator

Dilution Calculator

Complete Stock Solution Preparation Table

Phenylacetylglutamine-d5 Related Classifications

Keywords:

Your Recently Viewed Products:

Customer Review

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Phenylacetylglutamine-d₅ (Synonyms: NSC 203800-d₅; Phenylacetyl-L-glutamine-d₅)

Other Forms of Phenylacetylglutamine-d₅:

Phenylacetylglutamine-d₅ Related Antibodies

2 Publications Citing Use of MCE Phenylacetylglutamine-d₅

Phenylacetylglutamine-d₅ Related Classifications