2. Apoptosis
  3. MDM-2/p53
  4. PK095

PK095 is a p53 mutant stabilizer. PK095 can be used for research of cancer.

For research use only. We do not sell to patients.

PK095 Chemical Structure

PK095 Chemical Structure

CAS No. : 380314-37-4

Size Price Stock Quantity
1 mg USD 180 In-stock
5 mg USD 420 In-stock
10 mg USD 610 In-stock
50 mg   Get quote  
100 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

PK095 Related Antibodies

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Description

PK095 is a p53 mutant stabilizer. PK095 can be used for research of cancer[1].

Molecular Weight

378.45

Formula

C20H18N4O2S
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C1C=CN=C(N1)SCC(NC2=CC=C3C(C4=C(N3CC)C=CC=C4)=C2)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (264.24 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.6424 mL 13.2118 mL 26.4236 mL
5 mM 0.5285 mL 2.6424 mL 5.2847 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.6424 mL 13.2118 mL 26.4236 mL 66.0589 mL
5 mM 0.5285 mL 2.6424 mL 5.2847 mL 13.2118 mL
10 mM 0.2642 mL 1.3212 mL 2.6424 mL 6.6059 mL
15 mM 0.1762 mL 0.8808 mL 1.7616 mL 4.4039 mL
20 mM 0.1321 mL 0.6606 mL 1.3212 mL 3.3029 mL
25 mM 0.1057 mL 0.5285 mL 1.0569 mL 2.6424 mL
30 mM 0.0881 mL 0.4404 mL 0.8808 mL 2.2020 mL
40 mM 0.0661 mL 0.3303 mL 0.6606 mL 1.6515 mL
50 mM 0.0528 mL 0.2642 mL 0.5285 mL 1.3212 mL
60 mM 0.0440 mL 0.2202 mL 0.4404 mL 1.1010 mL
80 mM 0.0330 mL 0.1651 mL 0.3303 mL 0.8257 mL
100 mM 0.0264 mL 0.1321 mL 0.2642 mL 0.6606 mL
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PK095 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PK095380314-37-4PK 095PK-095MDM-2/p53CancerP53 mutantP53 stabilizerInhibitorinhibitorinhibit

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HY-153767
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