(R,R)-Nrf2 activator-1

Cat. No.: HY-145390A: FAQs
Data Sheet Handling Instructions Technical Support

(R,R)-Nrf2 activator-1 is the enantiomer of Nrf2 activator-1. Nrf2 activator-1 is a potent activator of NF-E2 related factor 2 (Nrf2). Nrf2 activator-1 has the potential for the research of COPD and other respiratory diseases, including asthma, Acute Lung Injury (ALI), Acute Respiratory Distress Syndrome (ARDS) and pulmonary fibrosis.

For research use only. We do not sell to patients.

(R,R)-Nrf2 activator-1 Chemical Structure

Size	Stock	Quantity
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
25 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	Get quote
100 mg	Get quote

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This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of (R,R)-Nrf2 activator-1:

Nrf2 activator-1 Get quote

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Biological Activity
Purity & Documentation
References
Customer Review

Description

Molecular Weight

578.68

Formula

C₃₀H₃₄N₄O₆S

SMILES

CCOC(C[C@H](C1=CC(CN2S(=O)(C3=CC=CC=C3O[C@@H](C2)C)=O)=C(C=C1)C)C4=CC(OC)=C(N(N=N5)C)C5=C4)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (172.81 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.7281 mL	8.6404 mL	17.2807 mL
5 mM	0.3456 mL	1.7281 mL	3.4561 mL
10 mM	0.1728 mL	0.8640 mL	1.7281 mL

View the Complete Stock Solution Preparation Table

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

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μL

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. James Francis Callahan, et al. Bisaryl amides as nrf2 regulators. Patent WO2018109647A1.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	1.7281 mL	8.6404 mL	17.2807 mL	43.2018 mL
	5 mM	0.3456 mL	1.7281 mL	3.4561 mL	8.6404 mL
	10 mM	0.1728 mL	0.8640 mL	1.7281 mL	4.3202 mL
	15 mM	0.1152 mL	0.5760 mL	1.1520 mL	2.8801 mL
	20 mM	0.0864 mL	0.4320 mL	0.8640 mL	2.1601 mL
	25 mM	0.0691 mL	0.3456 mL	0.6912 mL	1.7281 mL
	30 mM	0.0576 mL	0.2880 mL	0.5760 mL	1.4401 mL
	40 mM	0.0432 mL	0.2160 mL	0.4320 mL	1.0800 mL
	50 mM	0.0346 mL	0.1728 mL	0.3456 mL	0.8640 mL
	60 mM	0.0288 mL	0.1440 mL	0.2880 mL	0.7200 mL
	80 mM	0.0216 mL	0.1080 mL	0.2160 mL	0.5400 mL
	100 mM	0.0173 mL	0.0864 mL	0.1728 mL	0.4320 mL